Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

• An overview of the current understanding of bleeding and thrombosis in cirrhosis.• An
evidence-based justification for bleeding risk assessment in patients with cirrhosis before …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

1 ESGE recommends in patients with acute upper gastrointestinal hemorrhage (UGIH) the
use of the Glasgow–Blatchford Score (GBS) for pre-endoscopy risk stratification. Patients …

Background Whether prehospital administration of tranexamic acid increases the likelihood
of survival with a favorable functional outcome among patients with major trauma and …

Importance Tranexamic acid (TXA) is an efficient antifibrinolytic agent; however, concerns
remain about the potential adverse effects, particularly vascular occlusive events, that may …

Background Prophylactic administration of tranexamic acid has been associated with
reduced postpartum blood loss after cesarean delivery in several small trials, but evidence …

1 ESGE recommends that the initial assessment of patients presenting with acute lower
gastrointestinal bleeding should include: a history of co-morbidities and medications that …

Background Tranexamic acid (TXA) reduces surgical bleeding and reduces death from
bleeding after trauma and childbirth. However, its effects on thrombotic events and seizures …

Upper gastrointestinal bleeding is a common emergency presentation requiring prompt
resuscitation and management. Peptic ulcers are the most common cause of the condition …