Cationic antimicrobial polymers and their assemblies

AM Carmona-Ribeiro… - International journal of …, 2013 - mdpi.com
Cationic compounds are promising candidates for development of antimicrobial agents.
Positive charges attached to surfaces, particles, polymers, peptides or bilayers have been …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Biofilm formation and persistence on abiotic surfaces in the context of food and medical environments

M Abdallah, C Benoliel, D Drider, P Dhulster… - Archives of …, 2014 - Springer
The biofilm formation on abiotic surfaces in food and medical sectors constitutes a great
public health concerns. In fact, biofilms present a persistent source for pathogens, such as …

Synthetic antimicrobial polymers in combination therapy: tackling antibiotic resistance

R Namivandi-Zangeneh, EHH Wong… - ACS Infectious …, 2021 - ACS Publications
Antibiotic resistance is a critical global healthcare issue that urgently needs new effective
solutions. While small molecule antibiotics have been safeguarding us for nearly a century …

Emerging trends in macromolecular antimicrobials to fight multi-drug-resistant infections

AC Engler, N Wiradharma, ZY Ong, DJ Coady… - Nano Today, 2012 - Elsevier
Synthetic macromolecular antimicrobials are a highly promising class of therapeutics with
immense potential for combating multidrug resistant microbes. In contrast to conventional …

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes

K Chindera, M Mahato, A Kumar Sharma, H Horsley… - Scientific reports, 2016 - nature.com
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism
(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene …

Controlling macromolecular structures towards effective antimicrobial polymers

MS Ganewatta, C Tang - Polymer, 2015 - Elsevier
Drug resistance of pathogenic bacteria is a major global problem leading humanity towards
a pre-antibiotic era. Decline in the discovery of novel antibiotics and the lack of a resilient …

Effect of hydrophobic groups on antimicrobial and hemolytic activity: Develo** a predictive tool for ternary antimicrobial polymers

PT Phuong, S Oliver, J He, EHH Wong… - …, 2020 - ACS Publications
Antimicrobial polymers have emerged as a potential solution to the growing problem of
antimicrobial resistance. Although several studies have examined the effects of various …

Beyond the lipid-bilayer: interaction of polymers and nanoparticles with membranes

M Schulz, A Olubummo, WH Binder - Soft Matter, 2012 - pubs.rsc.org
Membranes can be fabricated either from lipid or polymer molecules, leading to the
formation of liposomes or polymersomes. In all types of liposomal membranes, the issue of …

Antimicrobial polymers as synthetic mimics of host‐defense peptides

K Kuroda, GA Caputo - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
Antibiotic‐resistant bacteria 'superbugs' are an emerging threat to public health due to the
decrease in effective antibiotics as well as the slowed pace of development of new …