Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …

Interoception is the sensing of internal bodily sensations. Interoception is an umbrella term
that encompasses (1) the afferent (body‐to‐brain) signaling through distinct neural and …

Fatigue is one of the most common symptoms in multiple sclerosis (MS), with a major impact
on patients' quality of life. Currently, treatment proceeds by trial and error with limited …

This paper outlines a hierarchical Bayesian framework for interoception,
homeostatic/allostatic control, and meta-cognition that connects fatigue and depression to …

The role of the cytokines and receptors of the IL-1 family in inflammation is well known.
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …

Chronic or persistent fatigue is a common, debilitating symptom of several diseases.
Persistent fatigue has been associated with low-grade inflammation in several models of …

Objective Early diagnosis and treatment initiation significantly influence long‐term disability
outcome in multiple sclerosis (MS). We aimed at identifying prodromal symptoms of MS in …

Background: Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative
disease. Over time, symptoms accumulate leading to increased disability of patients …

Background Fatigue is a complex and disabling symptom of Multiple Sclerosis (MS);
however, there is conflicting evidence of the relationship between fatigue and clinical …

Fatigue is a common, debilitating and often underestimated symptom in patients with
multiple sclerosis (MS). The exact pathophysiological mechanism of fatigue in MS is still …