Advances of medical nanorobots for future cancer treatments

X Kong, P Gao, J Wang, Y Fang, KC Hwang - Journal of Hematology & …, 2023 - Springer
Early detection and diagnosis of many cancers is very challenging. Late stage detection of a
cancer always leads to high mortality rates. It is imperative to develop novel and more …

Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

The history of nanoscience and nanotechnology: from chemical–physical applications to nanomedicine

S Bayda, M Adeel, T Tuccinardi, M Cordani, F Rizzolio - Molecules, 2019 - mdpi.com
Nanoscience breakthroughs in almost every field of science and nanotechnologies make life
easier in this era. Nanoscience and nanotechnology represent an expanding research area …

[HTML][HTML] Gene therapy in cancer treatment: why go nano?

C Roma-Rodrigues, L Rivas-García, PV Baptista… - Pharmaceutics, 2020 - mdpi.com
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

DNA origami nanostructures elicit dose‐dependent immunogenicity and are nontoxic up to high doses In vivo

CR Lucas, PD Halley, AA Chowdury, BK Harrington… - Small, 2022 - Wiley Online Library
DNA origami (DO) nanotechnology enables the construction of precise nanostructures
capable of functionalization with small molecule drugs, nucleic acids, and proteins …

[HTML][HTML] Micro/nanorobot: a promising targeted drug delivery system

M Hu, X Ge, X Chen, W Mao, X Qian, WE Yuan - Pharmaceutics, 2020 - mdpi.com
Micro/nanorobot, as a research field, has attracted interest in recent years. It has great
potential in medical treatment, as it can be applied in targeted drug delivery, surgical …

CRISPR–Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

E Lin-Shiao, WG Pfeifer, BR Shy… - Nucleic acids …, 2022 - academic.oup.com
DNA nanostructures are a promising tool to deliver molecular payloads to cells. DNA
origami structures, where long single-stranded DNA is folded into a compact nanostructure …

Palladium(II)‐η3‐Allyl Complexes Bearing N‐Trifluoromethyl N‐Heterocyclic Carbenes: A New Generation of Anticancer Agents that Restrain the Growth of High …

T Scattolin, E Bortolamiol, F Visentin… - … A European Journal, 2020 - Wiley Online Library
The first palladium organometallic compounds bearing N‐trifluoromethyl N‐heterocyclic
carbenes have been synthesized. These η3‐allyl complexes are potent antiproliferative …

Microfluidic organoids-on-a-chip: Quantum leap in cancer research

F Duzagac, G Saorin, L Memeo, V Canzonieri… - Cancers, 2021 - mdpi.com
Simple Summary Organoids, also known as self-organized 3D organ-like clusters, represent
almost a physiological system for studying cells, stem cells, tissues, and diseases, especially …

Aptamer-based targeted delivery systems for cancer treatment using DNA origami and DNA nanostructures

A Jabbari, E Sameiyan, E Yaghoobi… - International Journal of …, 2023 - Elsevier
Due to the limitations of conventional cancer treatment methods, nanomedicine has
appeared as a promising alternative, allowing improved drug targeting and decreased drug …