Different cognitive frailty models and health-and cognitive-related outcomes in older age: from epidemiology to prevention

F Panza, M Lozupone, V Solfrizzi… - Journal of …, 2018 - journals.sagepub.com
Frailty, a critical intermediate status of the aging process that is at increased risk for negative
health-related events, includes physical, cognitive, and psychosocial domains or …

Mechanisms of the anorexia of aging—a review

A Wysokiński, T Sobów, I Kłoszewska, T Kostka - Age, 2015 - Springer
Many, even healthy, older people fail to adequately regulate food intake and experience
loss of weight. Aging-associated changes in the regulation of appetite and the lack of hunger …

Prevalence and overlap of sarcopenia, frailty, cachexia and malnutrition in older medical inpatients

A Gingrich, D Volkert, E Kiesswetter, M Thomanek… - BMC geriatrics, 2019 - Springer
Background Sarcopenia, frailty, cachexia and malnutrition are widespread syndromes in
older people, characterized by loss of body tissue and related to poor outcome. The aim of …

Pathophysiology of anorexia in the cancer cachexia syndrome

CC Ezeoke, JE Morley - Journal of cachexia, sarcopenia and …, 2015 - Wiley Online Library
Anorexia is commonly present in persons with cancer and a major component of cancer
cachexia. There are multiple causes of anorexia in cancer. Peripherally, these can be due to …

Ageing is associated with decreases in appetite and energy intake—a meta-analysis in healthy adults

C Giezenaar, I Chapman, N Luscombe-Marsh… - Nutrients, 2016 - mdpi.com
It is not well recognized that in the elderly weight loss is more common than weight gain. The
aim of this analysis was to determine the effect of ageing on appetite (hunger/fullness) and …

Development of a model on determinants of malnutrition in aged persons: a MaNuEL project

D Volkert, E Kiesswetter, T Cederholm… - Gerontology and …, 2019 - journals.sagepub.com
In older persons, the origin of malnutrition is often multifactorial with a multitude of factors
involved. Presently, a common understanding about potential causes and their mode of …

[HTML][HTML] Frailty and sarcopenia: the new geriatric giants

JE Morley - Revista de investigacion clinica, 2016 - medigraphic.com
In the last decade, it has become clear that older persons who are frail or sarcopenic have
very high rates of functional deterioration, hospitalization, and death. Recently, it has …

Anorexia of ageing: a key component in the pathogenesis of both sarcopenia and cachexia

JE Morley - Journal of cachexia, sarcopenia and muscle, 2017 - Wiley Online Library
The anorexia of aging was first recognized as a physiological syndrome 30 years ago. Its
major causes are an alteration in fundal compliance with an increase in antral stretch and …

From sarcopenia to frailty: a road less traveled

JE Morley, S von Haehling, SD Anker… - Journal of cachexia …, 2014 - Springer
The physical frailty phenotype consists of fatigue, weight loss, and loss of muscle power.
Sarcopenia has been shown to be a major cause of frailty. Six societies including SCWD …

Nutritional vulnerability in older adults: a continuum of concerns

KNP Starr, SR McDonald, CW Bales - Current nutrition reports, 2015 - Springer
A nutritionally vulnerable older adult has a reduced physical reserve that limits the ability to
mount a vigorous recovery in the face of an acute health threat or stressor. Often, this …