Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Terpenoids are the most diverse group of specialized metabolites with numerous
applications. Their biosynthesis is based on the five-carbon isoprene building block and, as …

Natural products and their derivatives are widely used across various industries, particularly
pharmaceuticals. Modern engineered biosynthesis provides an alternative way of producing …

The spatial organization of genes within plant genomes can drive evolution of specialized
metabolic pathways. Terpenoids are important specialized metabolites in plants with diverse …

Terpene synthesis stands at the forefront of modern synthetic chemistry and represents the
state-of-the-art in the chemist's toolbox. Notwithstanding, these endeavors are inherently tied …

Sesterterpenoids are a very rare class of important natural products. Three new skeletal
spiro sesterterpenoids, named orientanoids A–C (1–3), were isolated from Hedyosmum …

Diterpene synthase VenA is responsible for assembling venezuelaene A with a unique 5-5-
6-7 tetracyclic skeleton from geranylgeranyl pyrophosphate. VenA also demonstrates …

Terpenoids constitute the biggest class of plant‐derived natural products with diverse
chemical structures and extensive biological activities. Interpreting enzyme functions and …

Many functionally promiscuous plant 2, 3-oxidosqualene cyclases (OSCs) have been found,
but complete functional resha** is rarely reported. In this study, we have identified two …

Genome mining of Aspergillus ustus 094102 enabled the discovery of a multiproduct
bifunctional terpene synthase (BTS), AuAS. Heterologous expression of AuAS led to the …