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Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …
Schizophrenia synaptic pathology and antipsychotic treatment in the framework of oxidative and mitochondrial dysfunction: translational highlights for the clinics and …
G De Simone, B Mazza, L Vellucci, A Barone… - Antioxidants, 2023 - mdpi.com
Schizophrenia is a worldwide mental illness characterized by alterations at dopaminergic
and glutamatergic synapses resulting in global dysconnectivity within and between brain …
and glutamatergic synapses resulting in global dysconnectivity within and between brain …
Transforming Healthcare with Nanomedicine: A SWOT Analysis of Drug Delivery Innovation
H Zhang, S Li, X Ma - Drug Design, Development and Therapy, 2024 - Taylor & Francis
Objective Nanomedicine represents a transformative approach in biomedical applications.
This study aims to delineate the application of nanomedicine in the biomedical field through …
This study aims to delineate the application of nanomedicine in the biomedical field through …
Comparative analysis of the pre-and post-medication effects of antipsychotic agents on the blood-based oxidative stress biomarkers in patients with schizophrenia: a …
M Yang, C Wang, G Zhao, D Kong, L Liu… - Current …, 2023 - benthamdirect.com
Objective: Studies have shown that oxidative stress (OS) is related to the pathophysiology of
schizophrenia (SCZ), but whether antipsychotics can induce OS has not been investigated …
schizophrenia (SCZ), but whether antipsychotics can induce OS has not been investigated …
Decrease in cognitive performance and increase of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios with higher doses of antipsychotics in women with …
Background We explored the relationship between symptoms, cognitive performance,
neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to …
neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to …
[HTML][HTML] Blood and urinary biomarkers of antipsychotic-induced metabolic syndrome
AK Khasanova, VS Dobrodeeva, NA Shnayder… - Metabolites, 2022 - mdpi.com
Metabolic syndrome (MetS) is a clustering of at least three of the following five medical
conditions: abdominal obesity, high blood pressure, high blood sugar, high serum …
conditions: abdominal obesity, high blood pressure, high blood sugar, high serum …
Differential impacts of endogenous antioxidants on clinical symptoms and cognitive function in acute and chronic schizophrenia patients
Background Impaired antioxidant defense is implicated in the pathophysiology of
schizophrenia, and superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) are …
schizophrenia, and superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) are …
Combination of UGT1A1 polymorphism and baseline plasma bilirubin levels in predicting the risk of antipsychotic-induced dyslipidemia in schizophrenia patients
C Lin, S Zhang, P Yang, B Zhang, W Guo, R Wu, Y Liu… - Schizophrenia, 2024 - nature.com
The prolonged usage of atypical antipsychotic drugs (AAPD) among individuals with
schizophrenia often leads to metabolic side effects such as dyslipidemia. These effects not …
schizophrenia often leads to metabolic side effects such as dyslipidemia. These effects not …
Antioxidants in neuropsychiatric disorder prevention: neuroprotection, synaptic regulation, microglia modulation, and neurotrophic effects
F Liu, Q Bai, W Tang, S Zhang, Y Guo, S Pan… - Frontiers in …, 2024 - frontiersin.org
Oxidative stress, caused by an imbalance between the generation of reactive oxygen
species (ROS) and the body's intrinsic antioxidant defenses, plays a critical role in …
species (ROS) and the body's intrinsic antioxidant defenses, plays a critical role in …
Effects of taurine in mice and zebrafish behavioral assays with translational relevance to schizophrenia
Background Altered redox state and developmental abnormalities in glutamatergic and
GABAergic transmission during development are linked to the behavioral changes …
GABAergic transmission during development are linked to the behavioral changes …