Signaling pathways in rheumatoid arthritis: implications for targeted therapy
Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …
progression leads to joint deformity and associated loss of function, which significantly …
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J **, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …
world. Although considerable progress has been made in the diagnosis, treatment and …
The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections
KB Rombouts, TAR van Merrienboer… - European journal of …, 2022 - Wiley Online Library
Background Aortic aneurysms (AA) are pathological dilations of the aorta, associated with
an overall mortality rate up to 90% in case of rupture. In addition to dilation, the aortic layers …
an overall mortality rate up to 90% in case of rupture. In addition to dilation, the aortic layers …
Modulating epigenetic modifications for cancer therapy
LJ Castro-Muñoz, E Vázquez Ulloa… - Oncology …, 2023 - spandidos-publications.com
Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …
earliest genomic aberrations occurring during cancer development and are closely related …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
[HTML][HTML] MicroRNA and cardiovascular diseases
HA Çakmak, M Demir - Balkan medical journal, 2020 - ncbi.nlm.nih.gov
Cardiovascular diseases are one of the most common causes of death in both develo**
and developed countries worldwide. Even though there have been improvements in primary …
and developed countries worldwide. Even though there have been improvements in primary …
The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
Recent progress in microRNA-based delivery systems for the treatment of human disease
Y Fu, J Chen, Z Huang - ExRNA, 2019 - Springer
MicroRNAs (miRNAs) are naturally occurring, small non-coding RNAs that mediate
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …
Competing endogenous RNAs, non-coding RNAs and diseases: an intertwined story
U Ala - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are responsible for RNA
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …
MicroRNA‐214‐3p enhances erastin‐induced ferroptosis by targeting ATF4 in hepatoma cells
T Bai, R Liang, R Zhu, W Wang… - Journal of cellular …, 2020 - Wiley Online Library
Primary liver cancer is the second most frequent cause of cancer‐related deaths.
Ferroptosis, a recognized form of regulated cell death, recently gains attention. MicroRNA …
Ferroptosis, a recognized form of regulated cell death, recently gains attention. MicroRNA …