Trends and targets in antiviral phototherapy

A Wiehe, JM O'Brien, MO Senge - Photochemical & Photobiological …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

Advances in antimicrobial photodynamic inactivation at the nanoscale

N Kashef, YY Huang, MR Hamblin - Nanophotonics, 2017 - degruyter.com
The alarming worldwide increase in antibiotic resistance amongst microbial pathogens
necessitates a search for new antimicrobial techniques, which will not be affected by, or …

Photosensitized singlet oxygen generation and detection: Recent advances and future perspectives in cancer photodynamic therapy

B Li, L Lin, H Lin, BC Wilson - Journal of biophotonics, 2016 - Wiley Online Library
Photodynamic therapy (PDT) uses photosensitizers and visible light in combination with
molecular oxygen to produce reactive oxygen species (ROS) that kill malignant cells by …

The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade

A Wiehe, MO Senge - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

[HTML][HTML] Insights into photodynamic therapy dosimetry: simultaneous singlet oxygen luminescence and photosensitizer photobleaching measurements

MT Jarvi, MS Patterson, BC Wilson - Biophysical journal, 2012 - cell.com
Photodynamic therapy (PDT) is generally based on the generation of highly reactive singlet
oxygen (1 O 2) through interactions of photosensitizer, light, and oxygen (3 O 2). These three …

Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success

BW Pogue, JT Elliott, SC Kanick… - Physics in Medicine …, 2016 - iopscience.iop.org
Photodynamic therapy (PDT) can be a highly complex treatment, with many parameters
influencing treatment efficacy. The extent to which dosimetry is used to monitor and …

Progress in transdermal drug delivery systems for cancer therapy

T Jiang, G Xu, G Chen, Y Zheng, B He, Z Gu - Nano Research, 2020 - Springer
Transdermal drug delivery is an appealing option except for oral and hypodermic
administration. With the advancement of skin penetration strategies, various anticancer …

Photodynamic therapy of melanoma skin cancer using carbon dot–chlorin e6–hyaluronate conjugate

S Beack, WH Kong, HS Jung, IH Do, S Han, H Kim… - Acta biomaterialia, 2015 - Elsevier
Despite wide application of photodynamic therapy (PDT) for the treatment of melanoma skin
cancers, there are strong biomedical unmet needs for the effective generation of singlet …

Singlet oxygen luminescence detection with a fiber-coupled superconducting nanowire single-photon detector

NR Gemmell, A McCarthy, B Liu, MG Tanner… - Optics express, 2013 - opg.optica.org
Direct monitoring of singlet oxygen (^ 1O_2) luminescence is a particularly challenging
infrared photodetection problem.^ 1O_2, an excited state of the oxygen molecule, is a crucial …

Effective near-infrared photodynamic therapy assisted by upconversion nanoparticles conjugated with photosensitizers

QQ Dou, CP Teng, E Ye, XJ Loh - International journal of …, 2015 - Taylor & Francis
A drug model photosensitizer–conjugated upconversion nanoparticles nanocomplex was
explored for application in near-infrared photodynamic therapy. As near-infrared penetrates …