Structural insights into type III secretion systems of the bacterial flagellum and injectisome
LJ Worrall, DD Majewski… - Annual Review of …, 2023 - annualreviews.org
Two of the most fascinating bacterial nanomachines—the broadly disseminated rotary
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …
Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells
Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …
Structure of the core of the type III secretion system export apparatus
Export of proteins through type III secretion systems is critical for motility and virulence of
many major bacterial pathogens. Three putative integral membrane proteins (FliP, FliQ, FliR) …
many major bacterial pathogens. Three putative integral membrane proteins (FliP, FliQ, FliR) …
Structural basis of torque generation in the bi-directional bacterial flagellar motor
H Hu, M Santiveri, N Wadhwa, HC Berg… - Trends in biochemical …, 2022 - cell.com
The flagellar stator unit is an oligomeric complex of two membrane proteins (MotA 5 B 2) that
powers bi-directional rotation of the bacterial flagellum. Harnessing the ion motive force …
powers bi-directional rotation of the bacterial flagellum. Harnessing the ion motive force …
T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly
The bacterial injectisome is a syringe-shaped macromolecular nanomachine utilized by
many pathogenic Gram-negative bacteria, including the causative agents of plague, typhoid …
many pathogenic Gram-negative bacteria, including the causative agents of plague, typhoid …
[HTML][HTML] The Shigella type III secretion system: an overview from top to bottom
Shigella comprises four species of human-restricted pathogens causing bacillary dysentery.
While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion …
While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion …
The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion
Protein secretion through type-three secretion systems (T3SS) is critical for motility and
virulence of many bacteria. Proteins are transported through an export gate containing three …
virulence of many bacteria. Proteins are transported through an export gate containing three …
Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system
The flagellum and the injectisome enable bacterial locomotion and pathogenesis,
respectively. These nanomachines assemble and function using a type III secretion system …
respectively. These nanomachines assemble and function using a type III secretion system …
[HTML][HTML] Structure and dynamics of the bacterial flagellar motor complex
S Nakamura, T Minamino - Biomolecules, 2024 - mdpi.com
Many bacteria swim in liquids and move over solid surfaces by rotating flagella. The
bacterial flagellum is a supramolecular protein complex that is composed of about 30 …
bacterial flagellum is a supramolecular protein complex that is composed of about 30 …
Cryo-EM structure of the Shigella type III needle complex
M Lunelli, A Kamprad, J Bürger, T Mielke… - PLoS …, 2020 - journals.plos.org
The Type III Secretion Systems (T3SS) needle complex is a conserved syringe-shaped
protein translocation nanomachine with a mass of about 3.5 MDa essential for the survival …
protein translocation nanomachine with a mass of about 3.5 MDa essential for the survival …