Soft amorphous materials are viscoelastic solids ubiquitously found around us, from clays
and cementitious pastes to emulsions and physical gels encountered in food or biomedical …

Biological processes, from morphogenesis to tumor invasion, spontaneously generate shear
stresses inside living tissue. The mechanisms that govern the transmission of mechanical …

Collective cell migration is an essential process throughout the lives of multicellular
organisms, for example in embryonic development, wound healing and tumour metastasis …

As develo** tissues grow in size and undergo morphogenetic changes, their material
properties may be altered. Such changes result from tension dynamics at cell contacts or …

Palpation utilizes the fact that solid breast tumours are stiffer than the surrounding tissue.
However, cancer cells tend to soften, which may enhance their ability to squeeze through …

Multicellular systems, such as epithelial cell collectives, undergo transitions similar to those
in inert physical systems like sand piles and foams. To remodel or maintain tissue …

The rheology of biological tissue is key to processes such as embryo development, wound
healing, and cancer metastasis. Vertex models of confluent tissue monolayers have …

Cell neighbor exchanges play a critical role in regulating tissue fluidity during epithelial
morphogenesis and repair. In vivo, these neighbor exchanges are often hindered by the …

We introduce an active version of the recently proposed finite Voronoi model of epithelial
tissue. The resultant Active Finite Voronoi (AFV) model enables the study of both confluent …

Large-scale tissue deformation during biological processes such as morphogenesis
requires cellular rearrangements. The simplest rearrangement in confluent cellular …