Non‐canonical roles of tRNAs and tRNA mimics in bacterial cell biology

A Katz, S Elgamal, A Rajkovic, M Ibba - Molecular microbiology, 2016 - Wiley Online Library
Transfer RNAs (tRNAs) are the macromolecules that transfer activated amino acids from
aminoacyl‐tRNA synthetases to the ribosome, where they are used for the mRNA guided …

[HTML][HTML] Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems

J Yuan, P O'Donoghue, A Ambrogelly, S Gundllapalli… - FEBS letters, 2010 - Elsevier
Selenocysteine and pyrrolysine, known as the 21st and 22nd amino acids, are directly
inserted into growing polypeptides during translation. Selenocysteine is synthesized via a …

An extension of the coevolution theory of the origin of the genetic code

M Di Giulio - Biology direct, 2008 - Springer
Background The coevolution theory of the origin of the genetic code suggests that the
genetic code is an imprint of the biosynthetic relationships between amino acids. However …

[KNYGA][B] Bioinformatics and the Cell

X ** tRNA synthetase inhibitors with 5-binding-mode classification
P Fang, M Guo - Life, 2015 - mdpi.com
Aminoacyl-tRNA synthetases (aaRSs) are enzymes that catalyze the transfer of amino acids
to their cognate tRNAs as building blocks for translation. Each of the aaRS families plays a …

Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis

T Suzuki, A Nakamura, K Kato, D Söll, I Tanaka… - Proceedings of the …, 2015 - pnas.org
Many prokaryotes lack a tRNA synthetase to attach asparagine to its cognate tRNAAsn, and
instead synthesize asparagine from tRNAAsn-bound aspartate. This conversion involves …

Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo

L Echevarria, P Clemente… - Biochemical …, 2014 - portlandpress.com
Translational accuracy depends on the correct formation of aminoacyl-tRNAs, which, in the
majority of cases, are produced by specific aminoacyl-tRNA synthetases that ligate each …

Indirect routes to aminoacyl-tRNA: The diversity of prokaryotic cysteine encoding systems

T Mukai, K Amikura, X Fu, D Söll, A Crnković - Frontiers in genetics, 2022 - frontiersin.org
Universally present aminoacyl-tRNA synthetases (aaRSs) stringently recognize their
cognate tRNAs and acylate them with one of the proteinogenic amino acids. However, some …