Microglia heterogeneity in the single-cell era
Microglia are resident immune cells in the central nervous system (CNS) that are capable of
carrying out prominent and various functions during development and adulthood under both …
carrying out prominent and various functions during development and adulthood under both …
Microglia emerge as central players in brain disease
MW Salter, B Stevens - Nature medicine, 2017 - nature.com
There has been an explosion of new findings recently giving us insights into the involvement
of microglia in central nervous system (CNS) disorders. A host of new molecular tools and …
of microglia in central nervous system (CNS) disorders. A host of new molecular tools and …
[HTML][HTML] GABA-receptive microglia selectively sculpt develo** inhibitory circuits
Microglia, the resident immune cells of the brain, have emerged as crucial regulators of
synaptic refinement and brain wiring. However, whether the remodeling of distinct synapse …
synaptic refinement and brain wiring. However, whether the remodeling of distinct synapse …
Microglia in depression: current perspectives
Major depressive disorder (MDD) is a prevalent psychiatric disease that involves
malfunctions of different cell types in the brain. Accumulating studies started to reveal that …
malfunctions of different cell types in the brain. Accumulating studies started to reveal that …
Bidirectional microglia–neuron communication in health and disease
Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
[HTML][HTML] Sha** neuronal fate: functional heterogeneity of direct microglia-neuron interactions
The functional contribution of microglia to normal brain development, healthy brain function,
and neurological disorders is increasingly recognized. However, until recently, the nature of …
and neurological disorders is increasingly recognized. However, until recently, the nature of …
Integrating neuroimmune systems in the neurobiology of depression
Data from clinical and preclinical studies indicate that immune dysregulation, specifically of
inflammatory processes, is associated with symptoms of major depressive disorder (MDD) …
inflammatory processes, is associated with symptoms of major depressive disorder (MDD) …
Microglia: dynamic mediators of synapse development and plasticity
Neuronal communication underlies all brain activity and the genesis of complex behavior.
Emerging research has revealed an unexpected role for immune molecules in the …
Emerging research has revealed an unexpected role for immune molecules in the …
Microglia across the lifespan: from origin to function in brain development, plasticity and cognition
Microglia are the only immune cells that permanently reside in the central nervous system
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …