Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets

R Chen, H Zhang, B Tang, Y Luo, Y Yang… - Signal transduction and …, 2024 - nature.com
The immune response holds a pivotal role in cardiovascular disease development. As
multifunctional cells of the innate immune system, macrophages play an essential role in …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Natural melanin/alginate hydrogels achieve cardiac repair through ROS scavenging and macrophage polarization

J Zhou, W Liu, X Zhao, Y **an, W Wu… - Advanced …, 2021 - Wiley Online Library
The efficacy of cardiac regenerative strategies for myocardial infarction (MI) treatment is
greatly limited by the cardiac microenvironment. The combination of reactive oxygen species …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Amorphizing metal selenides-based ROS biocatalysts at surface nanolayer toward ultrafast inflammatory diabetic wound healing

Y Deng, Y Gao, T Li, S **ao, M Adeli, RD Rodriguez… - ACS …, 2023 - ACS Publications
The microenvironments with high reactive-oxygen-species (ROS) levels, inflammatory
responses, and oxidative-stress effects in diabetic ulcer wounds, leading to poor …

Immune cells and immunotherapy for cardiac injury and repair

JG Rurik, H Aghajanian, JA Epstein - Circulation research, 2021 - ahajournals.org
Cardiac injury remains a major cause of morbidity and mortality worldwide. Despite
significant advances, a full understanding of why the heart fails to fully recover function after …

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

Multifunctional MXene-based bioactive materials for integrated regeneration therapy

J Ma, L Zhang, B Lei - ACS nano, 2023 - ACS Publications
The reconstruction engineering of tissue defects accompanied by major diseases including
cancer, infection, and inflammation is one of the important challenges in clinical medicine …

Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches

B López, S Ravassa, MU Moreno, GS José… - Nature Reviews …, 2021 - nature.com
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …