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Tumor angiogenesis and anti-angiogenic strategies for cancer treatment
Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …
ones and it is involved in both physiological and pathological processes of the body …
Notch signaling in vascular endothelial cells, angiogenesis, and tumor progression: an update and prospective
The Notch signaling pathway plays an essential role in a wide variety of biological
processes including cell fate determination of vascular endothelial cells and the regulation …
processes including cell fate determination of vascular endothelial cells and the regulation …
[HTML][HTML] Recent advances of organ-on-a-chip in cancer modeling research
X Liu, Q Su, X Zhang, W Yang, J Ning, K Jia, J **n, H Li… - Biosensors, 2022 - mdpi.com
Although many studies have focused on oncology and therapeutics in cancer, cancer
remains one of the leading causes of death worldwide. Due to the unclear molecular …
remains one of the leading causes of death worldwide. Due to the unclear molecular …
Tumour associated endothelial cells: origin, characteristics and role in metastasis and anti-angiogenic resistance
Tumour progression and metastasis remain the leading causes of cancer-related death
worldwide. Tumour angiogenesis is essential for tumour progression. The vasculature …
worldwide. Tumour angiogenesis is essential for tumour progression. The vasculature …
Helicobacter pylori promotes gastric cancer progression through the tumor microenvironment
L Zhu, Y Huang, H Li, S Shao - Applied Microbiology and Biotechnology, 2022 - Springer
Gastric cancer (GC) is a leading type of cancer. Although immunotherapy has yielded
important recent progress in the treatment of GC, the prognosis remains poor due to drug …
important recent progress in the treatment of GC, the prognosis remains poor due to drug …
[HTML][HTML] EWS/FLI1 characterization, activation, repression, target genes and therapeutic opportunities in Ewing sarcoma
Despite their clonal origins, tumors eventually develop into complex communities made up
of phenotypically different cell subpopulations, according to mounting evidence. Tumor cell …
of phenotypically different cell subpopulations, according to mounting evidence. Tumor cell …
[HTML][HTML] Metronomic anti-cancer therapy: A multimodal therapy governed by the tumor microenvironment
Simple Summary Metronomic chemotherapy with different mechanisms of action against
cancer cells and their microenvironment represents an exceptional holistic cancer treatment …
cancer cells and their microenvironment represents an exceptional holistic cancer treatment …
Spatial and temporal heterogeneity of digestive neuroendocrine neoplasms
P Bourdeleau, A Couvelard, M Ronot… - … in medical oncology, 2023 - journals.sagepub.com
Neuroendocrine neoplasms (NENs) are initially monoclonal neoplasms that progressively
become polyclonal, with very different genotypic and phenotypic characteristics leading to …
become polyclonal, with very different genotypic and phenotypic characteristics leading to …
Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling
Many cell-based therapies are challenged by the poor localization of introduced cells and
the use of biomaterial scaffolds with questionable biocompatibility or bio-functionality …
the use of biomaterial scaffolds with questionable biocompatibility or bio-functionality …
Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling
Breast cancer stem cells (BCSCs) are essential for cancer growth, metastasis and
recurrence. The regulatory mechanisms of BCSC interactions with the vascular niche within …
recurrence. The regulatory mechanisms of BCSC interactions with the vascular niche within …