Background Esophageal squamous cell carcinoma (ESCC) is a common invasive
malignancy worldwide with poor clinical outcomes. Increasing amount of long non-coding …

p21-Activated kinase 1 (PAK1) has attracted much attention as a potential therapeutic target
due to its central role in many oncogenic signaling pathways, its frequent dysregulation in …

Cell adhesion to the extracellular matrix (ECM) is important in a variety of physiological and
pathologic processes, including development, tumor invasion, and metastasis. Integrin …

The traditional Indian medicine, Ayurveda, provides insights and practical solutions towards
a healthy life style. Rasayana is a branch of Ayurveda known for preserving and promoting …

Breast cancer is a heterogeneous disease consisting of several subtypes. Among these
subtypes, triple negative breast cancer is particularly difficult to treat. This is due to a lack of …

Lung cancer represents the most common cause of cancer deaths in the world, constituting
around 11.6% of all new cancer cases and 18.4% of cancer-related deaths. The propensity …

Abstract P21 activated kinase 6 (PAK6) is a serine-threonine kinase with physiological
expression enriched in the brain and overexpressed in a number of human tumors. While …

Rationale: P21-activated kinase 6 (PAK6) is a member of the class II PAKs family, which is a
conserved family of serine/threonine kinases. Although the effects of PAK6 on many …

Most lung cancer deaths are related to metastases, which indicates the necessity of
detecting and inhibiting tumor cell dissemination. Here, we aimed to identify miRNAs …

Metabolic reprogramming is a hallmark of cancer and the link between oncogenes
activation, tumor supressors inactivation and bioenergetics modulation is well established …