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G-quadruplexes and their regulatory roles in biology
D Rhodes, HJ Lipps - Nucleic acids research, 2015 - academic.oup.com
Abstract 'If G-quadruplexes form so readily in vitro, Nature will have found a way of using
them in vivo'(Statement by Aaron Klug over 30 years ago). During the last decade, four …
them in vivo'(Statement by Aaron Klug over 30 years ago). During the last decade, four …
Fanconi anemia: current insights regarding epidemiology, cancer, and DNA repair
JD Peake, E Noguchi - Human genetics, 2022 - Springer
Fanconi anemia is a genetic disorder that is characterized by bone marrow failure, as well
as a predisposition to malignancies including leukemia and squamous cell carcinoma …
as a predisposition to malignancies including leukemia and squamous cell carcinoma …
I-motif DNA structures are formed in the nuclei of human cells
Human genome function is underpinned by the primary storage of genetic information in
canonical B-form DNA, with a second layer of DNA structure providing regulatory control. I …
canonical B-form DNA, with a second layer of DNA structure providing regulatory control. I …
Whole genome experimental maps of DNA G-quadruplexes in multiple species
G Marsico, VS Chambers, AB Sahakyan… - Nucleic acids …, 2019 - academic.oup.com
Genomic maps of DNA G-quadruplexes (G4s) can help elucidate the roles that these
secondary structures play in various organisms. Herein, we employ an improved version of a …
secondary structures play in various organisms. Herein, we employ an improved version of a …
Genome-wide map** of G-quadruplex structures with CUT&Tag
J Lyu, R Shao, PY Kwong Yung… - Nucleic acids …, 2022 - academic.oup.com
Single-stranded genomic DNA can fold into G-quadruplex (G4) structures or form DNA: RNA
hybrids (R loops). Recent evidence suggests that such non-canonical DNA structures affect …
hybrids (R loops). Recent evidence suggests that such non-canonical DNA structures affect …
G-rich DNA sequences can form four-stranded G-quadruplex (G4) secondary structures and
are linked to fundamental biological processes such as transcription, replication and …
are linked to fundamental biological processes such as transcription, replication and …
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
Following extensive evidence for the formation of four-stranded DNA G-quadruplex
structures in vitro, DNA G-quadruplexes have been observed within human cells. Although …
structures in vitro, DNA G-quadruplexes have been observed within human cells. Although …
Properties and biological impact of RNA G-quadruplexes: from order to turmoil and back
Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …