“Complimenting the complement”: mechanistic insights and opportunities for therapeutics in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and a
leading cause of death in the US and worldwide. HCC remains a global health problem and …
leading cause of death in the US and worldwide. HCC remains a global health problem and …
Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma
The global burden of hepatocellular carcinoma (HCC), one of the frequent causes of cancer-
related deaths worldwide, is rapidly increasing partly due to the limited treatment options …
related deaths worldwide, is rapidly increasing partly due to the limited treatment options …
hsa_circRNA_103636: potential novel diagnostic and therapeutic biomarker in Major depressive disorder
X Cui, W Niu, L Kong, M He, K Jiang, S Chen… - Biomarkers in …, 2016 - Taylor & Francis
Aim This study aimed to determine whether circular RNA (circRNA) molecules in peripheral
blood mononuclear cells (PBMCs) could be used as novel non-invasive biomarkers for …
blood mononuclear cells (PBMCs) could be used as novel non-invasive biomarkers for …
Components of the lectin pathway of complement in solid tumour cancers
M Cedzyński, AS Świerzko - Cancers, 2022 - mdpi.com
Simple Summary Cancer is a major cause of human deaths. The complement system is an
important branch of the innate immune response that can be activated via three distinct …
important branch of the innate immune response that can be activated via three distinct …
Development and validation of a three-gene prognostic signature for patients with hepatocellular carcinoma
B Li, W Feng, O Luo, T Xu, Y Cao, H Wu, D Yu… - Scientific reports, 2017 - nature.com
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death worldwide,
because recurrence often occurs in most HCC patients undergoing hepatectomy. It is …
because recurrence often occurs in most HCC patients undergoing hepatectomy. It is …
BBCancer: an expression atlas of blood-based biomarkers in the early diagnosis of cancers
Z Zuo, H Hu, Q Xu, X Luo, D Peng, K Zhu… - Nucleic Acids …, 2020 - academic.oup.com
The early detection of cancer holds the key to combat and control the increasing global
burden of cancer morbidity and mortality. Blood-based screenings using circulating DNAs …
burden of cancer morbidity and mortality. Blood-based screenings using circulating DNAs …
Serum glycoprotein markers in nonalcoholic steatohepatitis and hepatocellular carcinoma
P Ramachandran, G Xu, HH Huang… - Journal of Proteome …, 2022 - ACS Publications
Fatty liver disease progresses through stages of fat accumulation and inflammation to
nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis, and eventually hepatocellular …
nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis, and eventually hepatocellular …
Proteomic profiling of exosomes derived from plasma of HIV-infected alcohol drinkers and cigarette smokers
S Kodidela, Y Wang, BJ Patters, Y Gong… - Journal of Neuroimmune …, 2020 - Springer
Abuse of alcohol and tobacco could exacerbate HIV pathogenesis by transferring materials
through exosomes (small nanovesicles). Exosomes present a stable and accessible source …
through exosomes (small nanovesicles). Exosomes present a stable and accessible source …
Serum-derived exosomal proteins as potential candidate biomarkers for hepatocellular carcinoma
L Zhao, J Shi, L Chang, Y Wang, S Liu, Y Li… - ACS …, 2021 - ACS Publications
Hepatocellular carcinoma (HCC) is the most common form of hepatic malignancies. The
diagnosis of HCC remains challenging due to the low sensitivity and specificity of the …
diagnosis of HCC remains challenging due to the low sensitivity and specificity of the …
TNF‑α‑mediated epithelial‑to‑mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the fastest growing cause of cancer‑related deaths
globally. Epithelial‑to‑mesenchymal transition (EMT) is a cellular process that confers HCC …
globally. Epithelial‑to‑mesenchymal transition (EMT) is a cellular process that confers HCC …