Clinical instrumentation and applications of Raman spectroscopy

I Pence, A Mahadevan-Jansen - Chemical Society Reviews, 2016 - pubs.rsc.org
Clinical diagnostic devices provide new sources of information that give insight about the
state of health which can then be used to manage patient care. These tools can be as simple …

Label‐free molecular imaging of biological cells and tissues by linear and nonlinear Raman spectroscopic approaches

C Krafft, M Schmitt, IW Schie… - Angewandte Chemie …, 2017 - Wiley Online Library
Raman spectroscopy is an emerging technique in bioanalysis and imaging of biomaterials
owing to its unique capability of generating spectroscopic fingerprints. Imaging cells and …

[HTML][HTML] Salivary exosomal MicroRNA-486-5p and MicroRNA-10b-5p in oral and oropharyngeal squamous cell carcinoma

CI Faur, RC Roman, A Jurj, L Raduly, O Almășan… - Medicina, 2022 - mdpi.com
Background and Objectives: The research aimed at evaluating the capacity of salivary
exosomal miR-10b-5p and miR-486-5p for oral and oropharyngeal cancer detection …

A new detection method of oral and oropharyngeal squamous cell carcinoma based on multivariate analysis of surface enhanced Raman spectra of salivary …

CI Faur, C Dinu, V Toma, A Jurj, R Mărginean… - Journal of Personalized …, 2023 - mdpi.com
Raman spectroscopy recently proved a tremendous capacity to identify disease-specific
markers in various (bio) samples being a non-invasive, rapid, and reliable method for cancer …

Chemometric analysis of integrated FTIR and Raman spectra obtained by non-invasive exfoliative cytology for the screening of oral cancer

A Ghosh, S Raha, S Dey, K Chatterjee, AR Chowdhury… - Analyst, 2019 - pubs.rsc.org
FTIR spectroscopy and Raman spectroscopy of biological analytes are increasingly
explored as screening tools for early detection of cancer. In the present study, an integrated …

In vivo Raman spectroscopy for detection of oral neoplasia: A pilot clinical study

H Krishna, SK Majumder, P Chaturvedi… - Journal of …, 2014 - Wiley Online Library
We report a pilot study carried out to evaluate the applicability of in vivo Raman
spectroscopy for differential diagnosis of malignant and potentially malignant lesions of …

Biomedical applications of vibrational spectroscopy: Oral cancer diagnostics

HJ Byrne, I Behl, G Calado, O Ibrahim, M Toner… - … Acta Part A: Molecular …, 2021 - Elsevier
Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has
attracted increasing attention for biomedical applications. Proof of concept explorations for …

Recent advances in optical diagnosis of oral cancers: Review and future perspectives

SP Singh, O Ibrahim, HJ Byrne, JW Mikkonen… - Head & …, 2016 - Wiley Online Library
Optical diagnosis techniques offer several advantages over traditional approaches,
including objectivity, speed, and cost, and these label‐free, noninvasive methods have the …

The potential of Raman spectroscopy in the diagnosis of dysplastic and malignant oral lesions

O Ibrahim, M Toner, S Flint, HJ Byrne, FM Lyng - Cancers, 2021 - mdpi.com
Simple Summary Raman spectroscopy, a light scattering technique that provides the
biochemical fingerprint of a sample, was used on samples taken from patients with cancer …

In vivo Raman spectroscopy–assisted early identification of potential second primary/recurrences in oral cancers: an exploratory study

A Malik, A Sahu, SP Singh, A Deshmukh… - Head & …, 2017 - Wiley Online Library
Background Higher rates of local recurrences and second primaries, ascribable to field
cancerization, are known problem in oral cancers. The present study explored utility of …