Extending the landscape of omics technologies by pathomics
Tissue analysis is vital for investigating disease mechanisms and guiding diagnostics, eg, in
cancer, communicable or noncommunicable diseases. During the last decades …
cancer, communicable or noncommunicable diseases. During the last decades …
[HTML][HTML] Fenestrated Endothelial Cells across Organs: Insights into Kidney Function and Disease
X Mou, SM Leeman, Y Roye, C Miller… - International Journal of …, 2024 - mdpi.com
In the human body, the vascular system plays an indispensable role in maintaining
homeostasis by supplying oxygen and nutrients to cells and organs and facilitating the …
homeostasis by supplying oxygen and nutrients to cells and organs and facilitating the …
Deep learning applications for kidney histology analysis
Deep learning offers great opportunities to improve quantitative and qualitative kidney
histology analysis for research and clinical nephropathology diagnostics. Although exciting …
histology analysis for research and clinical nephropathology diagnostics. Although exciting …
[HTML][HTML] The Protective Role of Intermedin in Contrast-Induced Acute Kidney Injury: Enhancing Peritubular Capillary Endothelial Cell Adhesion and Integrity Through …
T Gao, R Gu, H Wang, L Li, B Zhang, J Hu… - International Journal of …, 2024 - mdpi.com
Contrast-induced acute kidney injury (CIAKI) is a common complication with limited
treatments. Intermedin (IMD), a peptide belonging to the calcitonin gene-related peptide …
treatments. Intermedin (IMD), a peptide belonging to the calcitonin gene-related peptide …
tRigon: an R package and Shiny App for integrative (path-) omics data analysis
DL Hölscher, M Goedertier, BM Klinkhammer… - BMC …, 2024 - Springer
Background Pathomics facilitates automated, reproducible and precise histopathology
analysis and morphological phenoty**. Similar to molecular omics, pathomics datasets …
analysis and morphological phenoty**. Similar to molecular omics, pathomics datasets …
Clinical relevance of computational pathology analysis of interplay between kidney microvasculature and interstitial microenvironment
Background: Interstitial fibrosis and tubular atrophy (IFTA), and density and shape of
peritubular capillaries (PTCs), are independently prognostic of disease progression. This …
peritubular capillaries (PTCs), are independently prognostic of disease progression. This …
The Quest for the Application of Artificial Intelligence to Whole Slide Imaging: Unique Prospective from New Advanced Tools
The introduction of machine learning in digital pathology has deeply impacted the field,
especially with the advent of whole slide image (WSI) analysis. In this review, we tried to …
especially with the advent of whole slide image (WSI) analysis. In this review, we tried to …
Clinical relevance of computationally derived tubular features: spatial relationships and the development of tubulointerstitial scarring in MCD/FSGS
Background Visual scoring of tubular damage has limitations in capturing the full spectrum
of structural changes and prognostic potential. We investigate if computationally quantified …
of structural changes and prognostic potential. We investigate if computationally quantified …
Long‐term, automated stool monitoring using a novel smart toilet: A feasibility study
Background Patients' report of bowel movement consistency is unreliable. We demonstrate
the feasibility of long‐term automated stool image data collection using a novel Smart Toilet …
the feasibility of long‐term automated stool image data collection using a novel Smart Toilet …
FUSION: A web-based application for in-depth exploration of multi-omics data with brightfield histology
S Border, RM Ferreira, N Lucarelli, D Manthey… - …, 2024 - pmc.ncbi.nlm.nih.gov
Spatial–OMICS technologies facilitate the interrogation of molecular profiles in the context of
the underlying histopathology and tissue microenvironment. Paired analysis of …
the underlying histopathology and tissue microenvironment. Paired analysis of …