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Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis
MJ Doenhoff, D Cioli, J Utzinger - Current opinion in infectious …, 2008 - journals.lww.com
Use of PZQ will increase in the foreseeable future, whether given alone or coadministered
with other anthelminthics in integrated control programmes. PZQ resistance remains a threat …
with other anthelminthics in integrated control programmes. PZQ resistance remains a threat …
Natural products as a source for treating neglected parasitic diseases
Infectious diseases caused by parasites are a major threat for the entire mankind, especially
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …
Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni
SD Melman, ML Steinauer… - PLoS neglected …, 2009 - journals.plos.org
Background The near exclusive use of praziquantel (PZQ) for treatment of human
schistosomiasis has raised concerns about the possible emergence of drug-resistant …
schistosomiasis has raised concerns about the possible emergence of drug-resistant …
Safety and immunogenicity of rSh28GST antigen in humans: phase 1 randomized clinical study of a vaccine candidate against urinary schistosomiasis
G Riveau, D Deplanque, F Remoue… - PLoS neglected …, 2012 - journals.plos.org
Background Treatment of urinary schistosomiasis by chemotherapy remains challenging
due to rapid re-infection and possibly to limited susceptibility to praziquantel treatment …
due to rapid re-infection and possibly to limited susceptibility to praziquantel treatment …
A review of the genetic determinants of praziquantel resistance in Schistosoma mansoni: Is praziquantel and intestinal schistosomiasis a perfect match?
S Summers, T Bhattacharyya, F Allan… - Frontiers in Tropical …, 2022 - frontiersin.org
Schistosomiasis is a neglected tropical disease (NTD) caused by parasitic trematodes
belonging to the Schistosoma genus. The mainstay of schistosomiasis control is the delivery …
belonging to the Schistosoma genus. The mainstay of schistosomiasis control is the delivery …
New approaches for understanding mechanisms of drug resistance in schistosomes
RM Greenberg - Parasitology, 2013 - cambridge.org
Schistosomes are parasitic flatworms that cause schistosomiasis, a neglected tropical
disease that affects hundreds of millions worldwide. Treatment and control of …
disease that affects hundreds of millions worldwide. Treatment and control of …
H1-antihistamines as antischistosomal drugs: in vitro and in vivo studies
RP Xavier, AC Mengarda, MP Silva, DB Roquini… - Parasites & …, 2020 - Springer
Background Schistosomiasis is a socioeconomically devastating parasitic infection afflicting
hundreds of millions of people and animals worldwide. It is the most important helminth …
hundreds of millions of people and animals worldwide. It is the most important helminth …
Licochalcone A-Loaded Solid Lipid Nanoparticles Improve Antischistosomal Activity In Vitro and In Vivo
LM Silva, DG Marconato, MP Nascimento da Silva… - …, 2021 - Taylor & Francis
Aim: To isolate licochalcone A (LicoA) from licorice, prepare LicoA-loaded solid lipid
nanoparticles (L-SLNs) and evaluate the L-SLNs in vitro and in vivo against Schistosoma …
nanoparticles (L-SLNs) and evaluate the L-SLNs in vitro and in vivo against Schistosoma …
[HTML][HTML] Novel therapeutic and prevention approaches for schistosomiasis
Schistosomiasis is a debilitating disease affecting approximately 600 million people in 74
develo** countries, with 800 million, mostly children at risk. To circumvent the threat of …
develo** countries, with 800 million, mostly children at risk. To circumvent the threat of …
A Recycled-Material-Based Electrochemical Eco-sensor for Sensitive Detection of Antischistosomal Drug Residues in Bovine-Derived Food Samples
Veterinary drug residues in food have emerged as an urgent threat to consumer safety.
Herein, we present the first square wave voltammetric method for the trace-level detection of …
Herein, we present the first square wave voltammetric method for the trace-level detection of …