Anisakis simplex: from Obscure Infectious Worm to Inducer of Immune Hypersensitivity

MT Audicana, MW Kennedy - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Infection of humans with the nematode worm parasite Anisakis simplex was first described in
the 1960s in association with the consumption of raw or undercooked fish. During the 1990s …

Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in …

K Kurose, E Sugiyama, Y Saito - Drug metabolism and …, 2012 - jstage.jst.go.jp
Drug lag, recently discussed extensively in Japan, can be divided into two phases: clinical
development time and application review time. The former factor is still an important problem …

Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies

OD Solberg, SJ Mack, AK Lancaster, RM Single… - Human immunology, 2008 - Elsevier
This paper presents a meta-analysis of high-resolution human leukocyte antigen (HLA)
allele frequency data describing 497 population samples. Most of the datasets were …

High-throughput DNA ty** of HLA-A,-B,-C, and-DRB1 loci by a PCR–SSOP–Luminex method in the Japanese population

Y Itoh, N Mizuki, T Shimada, F Azuma, M Itakura… - Immunogenetics, 2005 - Springer
We have developed a new high-throughput, high-resolution genoty** method for the
detection of alleles at the human leukocyte antigen (HLA)-A,-B,-C, and-DRB1 loci by …

HLA-VBSeq: accurate HLA ty** at full resolution from whole-genome sequencing data

N Nariai, K Kojima, S Saito, T Mimori, Y Sato, Y Kawai… - BMC genomics, 2015 - Springer
Background Human leucocyte antigen (HLA) genes play an important role in determining
the outcome of organ transplantation and are linked to many human diseases. Because of …

Immunogenetics as a tool in anthropological studies

A Sanchez‐Mazas, M Fernandez‐Viña… - …, 2011 - Wiley Online Library
The genes coding for the main molecules involved in the human immune system–
immunoglobulins, human leucocyte antigen (HLA) molecules and killer‐cell immunoglobulin …

Genetic structure of north-west Africa revealed by STR analysis

E Bosch, F Calafell, A Pérez-Lezaun… - European Journal of …, 2000 - nature.com
We have analysed a large set of autosomal short tandem repeat (STR) loci in several Arabic
and Berber-speaking groups from north-west Africa (ie Moroccan Arabs, northern-central …

Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits

D Comas, F Calafell, N Benchemsi, A Helal, G Lefranc… - Human Genetics, 2000 - Springer
An analysis of 11 Alu insertion polymorphisms (ACE, TPA25, PV92, APO, FXIIIB, D1, A25,
B65, HS2. 43, HS3. 23, and HS4. 65) has been performed in several NW African (Northern …

The genetic heterogeneity of Arab populations as inferred from HLA genes

A Hajjej, WY Almawi, A Arnaiz-Villena, L Hattab… - PloS one, 2018 - journals.plos.org
This is the first genetic anthropology study on Arabs in MENA (Middle East and North Africa)
region. The present meta-analysis included 100 populations from 36 Arab and non-Arab …

Local genetic variation of inflammatory bowel disease in Basque population and its effect in risk prediction

K Garcia-Etxebarria, O Merino, A Gaite-Reguero… - Scientific Reports, 2022 - nature.com
Inflammatory bowel disease (IBD) is characterised by chronic inflammation of the
gastrointestinal tract. Although its aetiology remains unknown, environmental and genetic …