A community-based transcriptomics classification and nomenclature of neocortical cell types
To understand the function of cortical circuits, it is necessary to catalog their cellular
diversity. Past attempts to do so using anatomical, physiological or molecular features of …
diversity. Past attempts to do so using anatomical, physiological or molecular features of …
[HTML][HTML] Establishing neuronal diversity in the spinal cord: a time and a place
The vertebrate spinal cord comprises multiple functionally distinct neuronal cell types
arranged in characteristic positions. During development, these different types of neurons …
arranged in characteristic positions. During development, these different types of neurons …
[HTML][HTML] Molecular architecture of the mouse nervous system
The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …
A harmonized atlas of mouse spinal cord cell types and their spatial organization
Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type
atlases of the mouse spinal cord have been published in recent years but have not been …
atlases of the mouse spinal cord have been published in recent years but have not been …
[HTML][HTML] A cellular taxonomy of the adult human spinal cord
The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding …
autonomic control, and movement. While animal models have advanced our understanding …
[HTML][HTML] An atlas of vagal sensory neurons and their molecular specialization
Sensory functions of the vagus nerve are critical for conscious perceptions and for
monitoring visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we …
monitoring visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we …
Genetic map** of cell type specificity for complex traits
K Watanabe, M Umićević Mirkov, CA de Leeuw… - Nature …, 2019 - nature.com
Single-cell RNA sequencing (scRNA-seq) data allows to create cell type specific
transcriptome profiles. Such profiles can be aligned with genome-wide association studies …
transcriptome profiles. Such profiles can be aligned with genome-wide association studies …
Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis
Paralysis occurring in amyotrophic lateral sclerosis (ALS) results from denervation of
skeletal muscle as a consequence of motor neuron degeneration. Interactions between …
skeletal muscle as a consequence of motor neuron degeneration. Interactions between …
Parallel ascending spinal pathways for affective touch and pain
S Choi, J Hachisuka, MA Brett, AR Magee, Y Omori… - Nature, 2020 - nature.com
The anterolateral pathway consists of ascending spinal tracts that convey pain, temperature
and touch information from the spinal cord to the brain,,–. Projection neurons of the …
and touch information from the spinal cord to the brain,,–. Projection neurons of the …