Accumulating evidence supports a link between sleep disorders, disturbed sleep, and
adverse brain health, ranging from stroke to subclinical cerebrovascular disease to cognitive …

Sleep is universal, tightly regulated, and its loss impairs cognition. But why does the brain
need to disconnect from the environment for hours every day? The synaptic homeostasis …

Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

It is assumed that synaptic strengthening and weakening balance throughout learning to
avoid runaway potentiation and memory interference. However, energetic and informational …

Various lifestyle and environmental factors are known to influence sleep. Increasingly,
evidence points to a role for the microbiota in regulating brain and behaviour. This article …

The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

Over more than a century of research has established the fact that sleep benefits the
retention of memory. In this review we aim to comprehensively cover the field of “sleep and …

This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

How sleep helps learning and memory remains unknown. We report in mouse motor cortex
that sleep after motor learning promotes the formation of postsynaptic dendritic spines on a …