Imaging mass spectrometry is a well-established technology that can easily and succinctly
communicate the spatial localization of molecules within samples. This review …

Multimodal mass spectrometry (MMS) incorporates an imaging modality with probe‐based
mass spectrometry (MS) to enable precise, targeted data acquisition and provide additional …

Specific locations of carbon–carbon double bonds (C═ C) in lipids often play an essential
role in biological processes, and there has been a booming development in C═ C …

Enzymes with high activity are readily produced through protein engineering, but
intentionally and efficiently engineering enzymes for an expanded substrate scope is a …

To meet the ever-increasing need for high-throughput screening in metabolic engineering,
information-rich, fast screening methods are needed. Mass spectrometry (MS) provides an …

The dominant strategy for tailoring the chain-length distribution of free fatty acids (FFA)
synthesized by heterologous hosts is expression of a selective acyl-acyl carrier protein …

Highlights•MS provides a label-free modality to screen microbial libraries.•Sample
preparation is critical to bridge culture formats and MS instrumentation.•Chromatography …

Creating controlled lipid unsaturation locations in oleochemicals can be a key to many
bioengineered products. However, evaluating the effects of modifications to the acyl-ACP …

Characterizing the chemicals within individual cells is an important analytical capability, with
mass spectrometry (MS) being one of the most chemically information-rich techniques …

Background Directed evolution is an iterative process of mutagenesis and phenotype
screening to achieve incremental improvements towards desired characteristics (Arnold …