Which scientist has never heard of glutathione (GSH)? This well-known low-molecular-
weight tripeptide is perhaps the most famous natural antioxidant. However, the interest in …

N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

Recent studies have demonstrated that bone marrow mesenchymal stem cells (BMSCs)
protect the injured neurons of spinal cord injury (SCI) from apoptosis while the underlying …

N-acetylcysteine (NAC), a precursor of cysteine and, thereby, glutathione (GSH), acts as an
antioxidant through a variety of mechanisms, including oxidant scavenging, GSH …

Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

Our previous studies reported that pharmacological maintenance of mitochondrial
bioenergetics after experimental spinal cord injury (SCI) provided functional …

The present study undertook a comprehensive assessment of the acute biochemical
oxidative stress parameters in both cellular and, notably, mitochondrial isolates following …

Acute central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI), and
spinal cord injury (SCI) present a grave health care challenge worldwide due to high …

Spinal cord injury (SCI) is a devastating disease that may lead to lifelong disability. Thus,
seeking for valid drugs that are beneficial to promoting axonal regrowth and elongation after …

Spinal cord injury (SCI) is characterized by an initial trauma followed by a progressive
cascade of damage referred to as secondary injury. A hallmark of secondary injury is …