[HTML][HTML] Pyrrolizidine alkaloids: chemistry, pharmacology, toxicology and food safety

R Moreira, DM Pereira, P Valentão… - International journal of …, 2018 - mdpi.com
Pyrrolizidine alkaloids (PA) are widely distributed in plants throughout the world, frequently
in species relevant for human consumption. Apart from the toxicity that these molecules can …

[HTML][HTML] Silage review: animal and human health risks from silage

F Driehuis, JM Wilkinson, Y Jiang, I Ogunade… - Journal of Dairy …, 2018 - Elsevier
Silage may contain several agents that are potentially hazardous to animal health, the safety
of milk or other animal food products, or both. This paper reviews published literature about …

EASL clinical practice guidelines: drug-induced liver injury

RJ Andrade, GP Aithal, ES Björnsson, N Kaplowitz… - Journal of …, 2019 - Elsevier
Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver
disorders faced by hepatologists, because of the myriad of drugs used in clinical practice …

Mode of action-based risk assessment of genotoxic carcinogens

A Hartwig, M Arand, B Epe, S Guth, G Jahnke… - Archives of …, 2020 - Springer
The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …

Fate, detection technologies and toxicity of heterocyclic PAHs in the aquatic and soil environments

P Ghosh, S Mukherji - Science of The Total Environment, 2023 - Elsevier
Heterocyclic polynuclear aromatic hydrocarbons (PAH) are characterized by higher
aqueous solubility and enhanced bioavailability due to presence of nitrogen, sulfur or …

Pyrrolizidine alkaloids: biosynthesis, biological activities and occurrence in crop plants

S Schramm, N Köhler, W Rozhon - Molecules, 2019 - mdpi.com
Pyrrolizidine alkaloids (PAs) are heterocyclic secondary metabolites with a typical
pyrrolizidine motif predominantly produced by plants as defense chemicals against …

[KNIHA][B] Alkaloids-secrets of life:: Aklaloid chemistry, biological significance, applications and ecological role

T Aniszewski - 2007 - books.google.com
Alkaloids, represent a group of interesting and complex chemical compounds, produced by
the secondary metabolism of living organisms in different biotopes. They are relatively …

[HTML][HTML] Food-borne chemical carcinogens and the evidence for human cancer risk

T Kobets, BPC Smith, GM Williams - Foods, 2022 - mdpi.com
Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …

The quest for modernisation of traditional Chinese medicine

Q Xu, R Bauer, BM Hendry, TP Fan, Z Zhao… - … and alternative medicine, 2013 - Springer
Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China.
Due to its worldwide use, potential impact on healthcare and opportunities for new drug …

Chemical markers for the quality control of herbal medicines: an overview

S Li, Q Han, C Qiao, J Song, C Lung Cheng, H Xu - Chinese medicine, 2008 - Springer
Selection of chemical markers is crucial for the quality control of herbal medicines, including
authentication of genuine species, harvesting the best quality raw materials, evaluation of …