[HTML][HTML] Factors affecting the performance of HRP2-based malaria rapid diagnostic tests

X Martiáñez-Vendrell, M Skjefte, R Sikka… - Tropical Medicine and …, 2022 - mdpi.com
The recent COVID-19 pandemic has profoundly impacted global malaria elimination
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …

Implementing COVID-19 (SARS-CoV-2) rapid diagnostic tests in sub-Saharan Africa: a review

J Jacobs, V Kühne, O Lunguya, D Affolabi… - Frontiers in …, 2020 - frontiersin.org
Introduction: For the COVID-19 (SARS-CoV-2) response, COVID-19 antigen (Ag), and
antibody (Ab) rapid diagnostic tests (RDTs) are expected to complement central molecular …

Malaria in under-five children: prevalence and multi-factor analysis of high-risk African countries

JV Mbishi, S Chombo, P Luoga, HJ Omary, HA Paulo… - BMC Public Health, 2024 - Springer
Background Malaria remains a significant public health challenge in Sub-Saharan Africa
(SSA), particularly affecting under-five (UN5) children. Despite global efforts to control the …

Widespread pfhrp2/3 deletions and HRP2-based false-negative results in southern Ethiopia

B Mekonen, S Dugassa, SM Feleke, B Dufera, B Gidisa… - Malaria Journal, 2024 - Springer
Abstract Background Rapid diagnostic tests (RDTs) play a significant role in expanding case
management in peripheral healthcare systems. Histidine-rich protein-2 (HRP2) antigen …

Rapid diagnosis and prognosis of malaria infection using a microfluidic point-of-care immunoassay

J Li, AM Saidi, K Seydel, PB Lillehoj - Biosensors and Bioelectronics, 2024 - Elsevier
Malaria is a major cause of illness and death worldwide. Rapid diagnostic tests are the most
widely used tool for detecting malaria infection, however, they only provide binary results …

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo

JB Parr, E Kieto, F Phanzu, P Mansiangi… - Scientific reports, 2021 - nature.com
The majority of Plasmodium falciparum malaria diagnoses in Africa are made using rapid
diagnostic tests (RDTs) that detect histidine-rich protein 2. Increasing reports of false …

Diagnosis of clinical malaria in endemic settings

R Varo, N Balanza, A Mayor… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction Malaria continues to be a major global health problem, with over 228 million
cases and 405,000 deaths estimated to occur annually. Rapid and accurate diagnosis of …

The malaria burden: a South African perspective

M Balmith, C Basson, SJ Brand - Journal of Tropical Medicine, 2024 - Wiley Online Library
Malaria is a deadly disease caused by protozoan pathogens of the Plasmodium parasite.
Transmission to humans occurs through the bite of an infected female Anopheles mosquito …

Laboratory detection of malaria antigens: a strong tool for malaria research, diagnosis, and epidemiology

M Plucinski, M Aidoo, E Rogier - Clinical Microbiology Reviews, 2021 - journals.asm.org
The identification and characterization of proteins produced during human infection with
Plasmodium spp. have guided the malaria community in research, diagnosis, epidemiology …