Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …

Many epithelial tumors grow in the vicinity of or metastasize to adipose tissue. As tumors
develop, crosstalk between adipose tissue and cancer cells leads to changes in adipocyte …

Obesity is recognized as a heterogeneous condition in which individuals with similar body
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …

The aging process is characterized by the chronic inflammatory status called
“inflammaging”, which shares major molecular and cellular features with the metabolism …

With worldwide expansion of the aging population, research on age-related pathologies is
receiving growing interest. In this review, we discuss current knowledge regarding the …

Women have more body fat than men, but in contrast to the deleterious metabolic
consequences of the central obesity typical of men, the pear-shaped body fat distribution of …

As a result of the rising epidemic of obesity, understanding body fat distribution and its
clinical implications is critical to timely treatment. Visceral adipose tissue is a hormonally …

Compelling evidence supports the concepts that gut microbiota actively promotes weight
gain and fat accumulation and sustains, indirectly, a condition of low-grade inflammation …

Abdominal (central) obesity strongly correlates with (hepatic) insulin resistance and type 2
diabetes. Among several hypotheses that have been formulated, the 'portal theory'proposes …

Recent advances in imaging techniques and understanding of differences in the molecular
biology of adipose tissue has rendered classical anatomy obsolete, requiring a new …