T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

Autoimmune diseases, such as Systemic Lupus Erythematosus (SLE) or Rheumatoid
Arthritis (RA) are characterized by the breakdown of immunological tolerance. Defects of …

Regulatory (Treg) cells are key regulators of inflammation and important for immune
tolerance and homeostasis. A major progress has been made in the identification and …

The end of twentieth century has introduced some changes into T helper (Th) cells division.
The identification of the new subpopulation of T helper cells producing IL-17 modified model …

Systemic lupus erythematosus (SLE) is an autoimmune disorder known for its complex
pathogenesis, in which cytokines play an essential role. It seems that the modulation of …

The view of CD4 T‐cell‐mediated immunity as a balance between distinct lineages of Th1
and Th2 cells has changed dramatically. Identification of the IL‐17 family of cytokines and of …

Since the characterization of CD4+ CD25+ regulatory T (Treg) cells in mice, significant
progress has been made in the definitions of the phenotype and the function of human Treg …

Inflammatory neuropathies are a heterogeneous group of rare diseases of the peripheral
nervous system that include acute and chronic diseases, such as Guillain-Barré syndrome …

Systemic lupus erythematosus (SLE) is a disease characterized by dysregulation and
hyperreactivity of the immune response at various levels, including hyperactivation of …

Pseudo-progression and flare-up phenomena constitute a novel diagnostic challenge in the
follow-up of patients treated with immune-oncology drugs. We present a case study on …