Recent development and application of constant pH molecular dynamics

W Chen, BH Morrow, C Shi, JK Shen - Molecular simulation, 2014 - Taylor & Francis
Solution pH is a critical environmental factor for chemical and biological processes. Over the
last decade, significant efforts have been made in the development of constant pH molecular …

Responsive self-assemblies based on fatty acids

AL Fameau, A Arnould, A Saint-Jalmes - Current opinion in colloid & …, 2014 - Elsevier
Fatty acids are anionic surfactants under their deprotonated forms. They are surfactants with
both biodegrability and low toxicity. Fatty acid molecules can self-assemble under various …

pH-responsive self-assembly of polysaccharide through a rugged energy landscape

BH Morrow, GF Payne, J Shen - Journal of the American Chemical …, 2015 - ACS Publications
Self-assembling polysaccharides can form complex networks with structures and properties
highly dependent on the sequence of triggering cues. Controlling the emergence of such …

Dynamic protonation dramatically affects the membrane permeability of drug-like molecules

Z Yue, C Li, GA Voth, JMJ Swanson - Journal of the American …, 2019 - ACS Publications
Permeability (P m) across biological membranes is of fundamental importance and a key
factor in drug absorption, distribution, and development. Although the majority of drugs will …

Decontamination of water co-polluted by copper, toluene and tetrahydrofuran using lauric acid

L Earnden, AG Marangoni, T Laredo, J Stobbs… - Scientific Reports, 2022 - nature.com
Co-contamination by organic solvents (eg, toluene and tetrahydrofuran) and metal ions (eg,
Cu2+) is common in industrial wastewater and in industrial sites. This manuscript describes …

[HTML][HTML] Experimental and simulation-based characterization of surfactant adsorption layers at fluid interfaces

E Schneck, J Reed, T Seki, Y Nagata… - Advances in Colloid and …, 2024 - Elsevier
Adsorption of surfactants to fluid interfaces occurs in numerous technological and daily-life
contexts. The coverage at the interface and other properties of the formed adsorption layers …

[HTML][HTML] A guide to the continuous constant pH molecular dynamics methods in Amber and CHARMM [Article v1. 0]

JA Henderson, R Liu, JA Harris, Y Huang… - Living journal of …, 2022 - ncbi.nlm.nih.gov
Like temperature and pressure, solution pH is an important environmental variable in
biomolecular simulations. Virtually all proteins depend on pH to maintain their structure and …

The Importance of Membrane Defects Lessons from Simulations

WFD Bennett, DP Tieleman - Accounts of chemical research, 2014 - ACS Publications
Conspectus The defects and pores within lipid membranes are scientifically interesting and
have a number of biological applications. Although lipid bilayers are extremely thin …

Interactions of surfactants with the bacterial cell wall and inner membrane: Revealing the link between aggregation and antimicrobial activity

P Sharma, R Vaiwala, S Parthasarathi, N Patil… - Langmuir, 2022 - ACS Publications
Surfactants with their intrinsic ability to solubilize lipid membranes are widely used as
antibacterial agents, and their interactions with the bacterial cell envelope are complicated …

Oleic acid phase behavior from molecular dynamics simulations

JJ Janke, WFD Bennett, DP Tieleman - Langmuir, 2014 - ACS Publications
Fatty acid aggregation is important for a number of diverse applications: from origins of life
research to industrial applications to health and disease. Experiments have characterized …