Ultrasound nanotheranostics: Toward precision medicine

Y Qin, X Geng, Y Sun, Y Zhao, W Chai, X Wang… - Journal of Controlled …, 2023 - Elsevier
Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

Making waves: how ultrasound-targeted drug delivery is changing pharmaceutical approaches

LJ Delaney, S Isguven, JR Eisenbrey, NJ Hickok… - Materials …, 2022 - pubs.rsc.org
Administration of drugs through oral and intravenous routes is a mainstay of modern
medicine, but this approach suffers from limitations associated with off-target side effects and …

Formulation strategies to provide oxygen-release to contrast local hypoxia for transplanted islets

Z Wang, Z Jiang, R Lu, L Kou, YZ Zhao… - European Journal of …, 2023 - Elsevier
Islet transplantation refers to the transfusion of healthy islet cells into the diabetic recipients
and reconstruction of their endogenous insulin secretion to achieve insulin independence. It …

Tumoral oxygenation and biodistribution of Lonidamine oxygen microbubbles following localized ultrasound-triggered delivery

Q Lacerda, A Rochani, B Oeffinger, JB Liu… - International journal of …, 2022 - Elsevier
Prior work has shown that microbubble-assisted delivery of oxygen improves tumor
oxygenation and radiosensitivity, albeit over a limited duration. Lonidamine (LND) has been …

Development of a dual drug-loaded, surfactant-stabilized contrast agent containing oxygen

R Patel, Q Lacerda, BE Oeffinger, JR Eisenbrey… - Polymers, 2022 - mdpi.com
Co-delivery of cancer therapeutics improves efficacy and encourages synergy, but delivery
faces challenges, including multidrug resistance and spatiotemporal distribution of …

Develo** Ultrasound Contrast Agents to Deliver siRNA to Spinal Cord Injury

BE Oeffinger - 2024 - search.proquest.com
Spinal cord injury (SCI) initiates a complex biological response and leads to the disruption of
motor and sensory signals between the brain and the peripheral body at and below the level …

[BOOK][B] Ultrasound-Sensitive Microbubble Approaches for Overcoming Tumor Hypoxia in Head and Neck Squamous Cell Carcinoma

QR Lacerda - 2023 - search.proquest.com
Several studies have shown that tumor hypoxia is directly associated with a poor prognosis
in patients with advanced head and neck squamous cell carcinoma (HNSCC). Hypoxic …