2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024‏ - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022‏ - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023‏ - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

A brief history of human disease genetics

M Claussnitzer, JH Cho, R Collins, NJ Cox… - Nature, 2020‏ - nature.com
A primary goal of human genetics is to identify DNA sequence variants that influence
biomedical traits, particularly those related to the onset and progression of human disease …

Objectives, design and main findings until 2020 from the Rotterdam Study

MA Ikram, G Brusselle, M Ghanbari… - European journal of …, 2020‏ - Springer
Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …

Evaluating the promise of inclusion of African ancestry populations in genomics

AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020‏ - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

[HTML][HTML] The HERITAGE Family Study: a review of the effects of exercise training on cardiometabolic health, with insights into molecular transducers

MA Sarzynski, TK Rice, JP Després… - Medicine and science …, 2022‏ - ncbi.nlm.nih.gov
The aim of the HERITAGE Family Study was to investigate individual differences in response
to a standardized endurance exercise program, the role of familial aggregation, and the …

Hypertension genetics past, present and future applications

KJ Olczak, V Taylor‐Bateman… - Journal of internal …, 2021‏ - Wiley Online Library
Essential hypertension is a complex trait where the underlying aetiology is not completely
understood. Left untreated it increases the risk of severe health complications including …

Gene-lifestyle interactions in the genomics of human complex traits

V Laville, T Majarian, YJ Sung, K Schwander… - European Journal of …, 2022‏ - nature.com
The role and biological significance of gene-environment interactions in human traits and
diseases remain poorly understood. To address these questions, the CHARGE Gene …

Genomic innovation in early life cardiovascular disease prevention and treatment

C Li, Y Pan, R Zhang, Z Huang, D Li, Y Han… - Circulation …, 2023‏ - Am Heart Assoc
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality globally.
Although CVD events do not typically manifest until older adulthood, CVD develops …