Mitochondria are the key source of ATP that fuels cellular functions, and they are also central
in cellular signaling, cell division and apoptosis. Dysfunction of mitochondria has been …

Research over the past decade has extended the prevailing view of the mitochondrion to
include functions well beyond the generation of cellular energy. It is now recognized that …

During transduction of an apoptotic (death) signal into the cell, there is an alteration in the
permeability of the membranes of the cell's mitochondria, which causes the translocation of …

This review deals with the permeability transition (PT) of isolated mitochondria, a field
spawned at the very beginning of mitochondrial research by the observation that the …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Expression of the cystic fibrosis transmembrane conductance regulator (CFTR) generates
adenosine 3′, 5′-monophosphate (cAMP)-regulated chloride channels, indicating that …

ALL cellular organisms respond to vibration, touch, gravity or changes in osmolarity,
although the molecules on which such mechanosensations depend are unknown …

SUMMARY A comprehensive classification system for transmembrane molecular
transporters has been developed and recently approved by the transport panel of the …

Palacı́n, Manuel, Raúl Estévez, Joan Bertran, and Antonio Zorzano. Molecular Biology of
Mammalian Plasma Membrane Amino Acid Transporters. Physiol. Rev. 78: 969–1054, 1998 …

Voltage-dependent anion channel (VDAC), the most abundant mitochondrial outer
membrane protein, is important for a variety of mitochondrial functions including metabolite …