Ion mobility spectrometry: fundamental concepts, instrumentation, applications, and the road ahead

JN Dodds, ES Baker - Journal of the American Society for Mass …, 2019 - ACS Publications
Ion mobility spectrometry (IMS) is a rapid separation technique that has experienced
exponential growth as a field of study. Interfacing IMS with mass spectrometry (IMS-MS) …

[HTML][HTML] Software tools and approaches for compound identification of LC-MS/MS data in metabolomics

I Blaženović, T Kind, J Ji, O Fiehn - Metabolites, 2018 - mdpi.com
The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics

Z Zhou, M Luo, X Chen, Y Yin, X **ong, R Wang… - Nature …, 2020 - nature.com
The metabolome includes not just known but also unknown metabolites; however,
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …

Recommendations for reporting ion mobility Mass Spectrometry measurements

V Gabelica, AA Shvartsburg, C Afonso… - Mass spectrometry …, 2019 - Wiley Online Library
Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

Collision cross section compendium to annotate and predict multi-omic compound identities

JA Picache, BS Rose, A Balinski, KL Leaptrot… - Chemical …, 2019 - pubs.rsc.org
Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic
workflows by providing an additional separation dimension as well as a parameter for …

Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass spectrometry reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Development and application of a multidimensional database for the detection of quaternary ammonium compounds and their phase I hepatic metabolites in humans

R Nguyen, RP Seguin, DH Ross, P Chen… - Environmental …, 2024 - ACS Publications
The COVID-19 pandemic has led to significantly increased human exposure to the widely
used disinfectants quaternary ammonium compounds (QACs). Xenobiotic metabolism …

High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations

DG Delafield, G Lu, CJ Kaminsky, L Li - TrAC Trends in Analytical …, 2022 - Elsevier
Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …

[HTML][HTML] Ion mobility spectrometry in food analysis: Principles, current applications and future trends

M Hernández-Mesa, D Ropartz, AM García-Campaña… - Molecules, 2019 - mdpi.com
In the last decade, ion mobility spectrometry (IMS) has reemerged as an analytical
separation technique, especially due to the commercialization of ion mobility mass …

Breaking down structural diversity for comprehensive prediction of ion-neutral collision cross sections

DH Ross, JH Cho, L Xu - Analytical chemistry, 2020 - ACS Publications
Identification of unknowns is a bottleneck for large-scale untargeted analyses like
metabolomics or drug metabolite identification. Ion mobility-mass spectrometry (IM-MS) …