Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the
global health care industry. While a small minority of joint arthroplasties will become …

Background: The search for a single standard reference test for determining periprosthetic
joint infection (PJI) through analysis of synovial fluid has yielded numerous biomarkers as …

Background: Next-generation sequencing is a well-established technique for sequencing of
DNA and has recently gained attention in many fields of medicine. Our aim was to evaluate …

A 62-year-old woman with osteoarthritis presents with a 7-month history of progressively
worsening left hip pain radiating to the groin, 8 months after undergoing total left-hip …

Background For the diagnosis of prosthetic joint infection, real evidence-based guidelines to
aid clinicians in choosing the most accurate diagnostic strategy are lacking. Aim and …

Consensus: Clinically, PJI may be present without meeting these criteria, specifically in the
case of less virulent organisms (eg Propionibacterium acnes). Synovial leukocyte esterase …

The microbiological diagnosis of periprosthetic joint infection (PJI) is crucial for successful
antimicrobial treatment. Cultures have limited sensitivity, especially in patients receiving …

Background The alpha-defensin test has been previously demonstrated to be highly
accurate in the diagnosis of prosthetic joint infection (PJI), nearly matching the …

JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical Techniques Open Access
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Aims The diagnosis of periprosthetic joint infection can be difficult due to the high rate of
culture-negative infections. The aim of this study was to assess the use of next-generation …