The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Glycosylation is a major regulator of phenylpropanoid availability and biological activity in plants

J Le Roy, B Huss, A Creach, S Hawkins… - Frontiers in plant …, 2016 - frontiersin.org
The phenylpropanoid pathway in plants is responsible for the biosynthesis of a huge amount
of secondary metabolites derived from phenylalanine and tyrosine. Both flavonoids and …

Plant secondary metabolism linked glycosyltransferases: An update on expanding knowledge and scopes

P Tiwari, RS Sangwan, NS Sangwan - Biotechnology Advances, 2016 - Elsevier
The multigene family of enzymes known as glycosyltransferases or popularly known as GTs
catalyze the addition of carbohydrate moiety to a variety of synthetic as well as natural …

Biologically active compounds and pharmacological activities of species of the genus Crocus: A review

O Mykhailenko, V Kovalyov, O Goryacha, L Ivanauskas… - Phytochemistry, 2019 - Elsevier
The present article is the first comprehensive review on the chemical composition and
pharmacological activities of the raw materials of Crocus species. In the present review, data …

[HTML][HTML] Therapeutic application and toxicity associated with Crocus sativus (saffron) and its phytochemicals

AK Wani, J Singh, S Shukla - Pharmacological Research-Modern …, 2022 - Elsevier
Saffron, a Crocus sativus L. derivative, has been recognized for its medical benefits since
ancient times. Besides being an active flavoring and coloring agent in several food items …

Identification of phenolic markers for saffron authenticity and origin: An untargeted metabolomics approach

B Senizza, G Rocchetti, S Ghisoni, M Busconi… - Food Research …, 2019 - Elsevier
Saffron is a high-quality and expensive spice being widely subjected to adulteration. An
UHPLC-ESI/QTOF-MS metabolomic-based approach was therefore used to investigate the …

Saffron: its phytochemistry, developmental processes, and biotechnological prospects

O Ahrazem, A Rubio-Moraga, SG Nebauer… - Journal of agricultural …, 2015 - ACS Publications
The present state of knowledge concerning developmental processes and the secondary
metabolism of saffron, Crocus sativus L.(Iridaceae), along with the genes involved in these …

Comprehensive transcriptome analysis of Crocus sativus for discovery and expression of genes involved in apocarotenoid biosynthesis

SA Baba, T Mohiuddin, S Basu, MK Swarnkar… - BMC genomics, 2015 - Springer
Background Crocus sativus stigmas form rich source of apocarotenoids like crocin,
picrocrocin and saffranal which besides imparting color, flavour and aroma to saffron spice …

Bioactivity and applications of saffron floral bio-residues (tepals): a natural by-product for the food, pharmaceutical, and cosmetic industries

N Belyagoubi-Benhammou, L Belyagoubi… - Critical Reviews in …, 2024 - Taylor & Francis
Saffron “Crocus sativus” is a plant of the Iridaceae family. Its therapeutic virtues have been
known since antiquity; it is used in traditional medicine and culinary preparations. It is also …

Biochemical and Molecular Characterization of a Flavonoid 3-O-glycosyltransferase Responsible for Anthocyanins and Flavonols Biosynthesis in Freesia hybrida

W Sun, L Liang, X Meng, Y Li, F Gao, X Liu… - Frontiers in Plant …, 2016 - frontiersin.org
The glycosylation of flavonoids increases their solubility and stability in plants. Flowers
accumulate anthocyanidin and flavonol glycosides which are synthesized by UDP-sugar …