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Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases
T Sakuragi, S Nagata - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …
environment or partition cells into distinct compartments. These membranes are lipid …
Don't eat me/eat me signals as a novel strategy in cancer immunotherapy
Cancer stands as one of the prominent global causes of death, with its incidence burden
continuously increasing, leading to a substantial rise in mortality rates. Cancer treatment has …
continuously increasing, leading to a substantial rise in mortality rates. Cancer treatment has …
[HTML][HTML] Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia
COVID-19 is a disease with unique characteristics that include lung thrombosis, frequent
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
Structural and functional consequences of reversible lipid asymmetry in living membranes
Maintenance of lipid asymmetry across the two leaflets of the plasma membrane (PM)
bilayer is a ubiquitous feature of eukaryotic cells. Loss of this asymmetry has been widely …
bilayer is a ubiquitous feature of eukaryotic cells. Loss of this asymmetry has been widely …
[HTML][HTML] Sperm lipid markers of male fertility in mammals
Sperm plasma membrane lipids are essential for the function and integrity of mammalian
spermatozoa. Various lipid types are involved in each key step within the fertilization …
spermatozoa. Various lipid types are involved in each key step within the fertilization …
Putting the brakes on phagocytosis:“don't‐eat‐me” signaling in physiology and disease
SM Kelley, KS Ravichandran - EMBO reports, 2021 - embopress.org
Timely removal of dying or pathogenic cells by phagocytes is essential to maintaining host
homeostasis. Phagocytes execute the clearance process with high fidelity while sparing …
homeostasis. Phagocytes execute the clearance process with high fidelity while sparing …
Flagging fusion: Phosphatidylserine signaling in cell–cell fusion
Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a
common step, cell–cell fusion. Recent years have brought about considerable progress in …
common step, cell–cell fusion. Recent years have brought about considerable progress in …
Phosphatidylserine exposure in living cells
HW Shin, H Takatsu - Critical reviews in biochemistry and …, 2020 - Taylor & Francis
P4-ATPases, a subfamily of P-type ATPases, translocate cell membrane phospholipids from
the exoplasmic/luminal leaflet to the cytoplasmic leaflet to generate and maintain membrane …
the exoplasmic/luminal leaflet to the cytoplasmic leaflet to generate and maintain membrane …
The fertilization enigma: how sperm and egg fuse
VE Deneke, A Pauli - Annual review of cell and developmental …, 2021 - annualreviews.org
Fertilization is a multistep process that culminates in the fusion of sperm and egg, thus
marking the beginning of a new organism in sexually reproducing species. Despite its …
marking the beginning of a new organism in sexually reproducing species. Despite its …
Intraovarian injection of platelet-rich plasma in assisted reproduction: too much too soon?
The prospect of ovarian rejuvenation offers the tantalising prospect of treating age-related
declines in fertility or in pathological conditions such as premature ovarian failure. The …
declines in fertility or in pathological conditions such as premature ovarian failure. The …