Tauopathies: new perspectives and challenges
Y Zhang, KM Wu, L Yang, Q Dong, JT Yu - Molecular neurodegeneration, 2022 - Springer
Background Tauopathies are a class of neurodegenerative disorders characterized by
neuronal and/or glial tau-positive inclusions. Main body Clinically, tauopathies can present …
neuronal and/or glial tau-positive inclusions. Main body Clinically, tauopathies can present …
Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer disease pathology
Importance Phosphorylated tau (p-tau) is a specific blood biomarker for Alzheimer disease
(AD) pathology, with p-tau217 considered to have the most utility. However, availability of p …
(AD) pathology, with p-tau217 considered to have the most utility. However, availability of p …
Plasma biomarkers of Alzheimer's disease: a review of available assays, recent developments, and implications for clinical practice
Recently, low-sensitive plasma assays have been replaced by new ultra-sensitive assays
such as single molecule enzyme-linked immunosorbent assay (Simoa), the Mesoscale …
such as single molecule enzyme-linked immunosorbent assay (Simoa), the Mesoscale …
Plasma biomarker strategy for selecting patients with Alzheimer disease for antiamyloid immunotherapies
Importance Antiamyloid immunotherapies against Alzheimer disease (AD) are emerging.
Scalable, cost-effective tools will be needed to identify amyloid β (Aβ)–positive patients …
Scalable, cost-effective tools will be needed to identify amyloid β (Aβ)–positive patients …
Biomarker-based prediction of longitudinal tau positron emission tomography in Alzheimer disease
Importance There is currently no consensus as to which biomarkers best predict longitudinal
tau accumulation at different clinical stages of Alzheimer disease (AD). Objective To …
tau accumulation at different clinical stages of Alzheimer disease (AD). Objective To …
Equivalence of plasma p‐tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease
INTRODUCTION Plasma biomarkers are promising tools for Alzheimer's disease (AD)
diagnosis, but comparisons with more established biomarkers are needed. METHODS We …
diagnosis, but comparisons with more established biomarkers are needed. METHODS We …
Global neuropathologic severity of Alzheimer's disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels
Background Advances in ultrasensitive detection of phosphorylated tau (p-tau) in plasma
has enabled the use of blood tests to measure Alzheimer's disease (AD) biomarker …
has enabled the use of blood tests to measure Alzheimer's disease (AD) biomarker …
Evaluation of plasma biomarkers for a/T/N classification of Alzheimer disease among adults of Caribbean Hispanic ethnicity
Importance Cerebrospinal fluid (CSF) and plasma biomarkers can detect biological
evidence of Alzheimer disease (AD), but their use in low-resource environments and among …
evidence of Alzheimer disease (AD), but their use in low-resource environments and among …
Detection of brain tau pathology in Down syndrome using plasma biomarkers
S Janelidze, BT Christian, J Price, C Laymon… - JAMA …, 2022 - jamanetwork.com
Importance Novel plasma biomarkers, especially phosphorylated tau (p-tau), can detect
brain tau aggregates in Alzheimer disease. Objective To determine which plasma biomarker …
brain tau aggregates in Alzheimer disease. Objective To determine which plasma biomarker …
Long COVID as a tauopathy: of “Brain Fog” and “Fusogen Storms”
A Sfera, L Rahman… - International Journal of …, 2023 - mdpi.com
Long COVID, also called post-acute sequelae of SARS-CoV-2, is characterized by a
multitude of lingering symptoms, including impaired cognition, that can last for many months …
multitude of lingering symptoms, including impaired cognition, that can last for many months …