Double emulsion solvent evaporation techniques used for drug encapsulation
Double emulsions are complex systems, also called “emulsions of emulsions”, in which the
droplets of the dispersed phase contain one or more types of smaller dispersed droplets …
droplets of the dispersed phase contain one or more types of smaller dispersed droplets …
Recent advances in protein and peptide drug delivery: a special emphasis on polymeric nanoparticles
Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …
most commonly em-ployed method of administration for therapeutic proteins and peptides …
Gold nanoparticle should understand protein corona for being a clinical nanomaterial
Gold nanoparticles (AuNPs) have attracted great attention in biomedical fields due to their
unique properties. However, there are few reports on clinical trial of these nanoparticles. In …
unique properties. However, there are few reports on clinical trial of these nanoparticles. In …
The biomolecular corona of nanoparticles in circulating biological media
D Pozzi, G Caracciolo, L Digiacomo, V Colapicchioni… - Nanoscale, 2015 - pubs.rsc.org
When nanoparticles come into contact with biological media, they are covered by a
biomolecular 'corona', which confers a new identity to the particles. In all the studies reported …
biomolecular 'corona', which confers a new identity to the particles. In all the studies reported …
Aerosol pulmonary immune engineering
ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …
Prediction of nanoparticles-cell association based on corona proteins and physicochemical properties
Cellular association of nanoparticles (NPs) in biological fluids is affected by proteins
adsorbed onto the NP surface, forming a “protein corona”, thereby impacting cellular …
adsorbed onto the NP surface, forming a “protein corona”, thereby impacting cellular …
Emulsion techniques for the production of pharmacological nanoparticles
Nanoparticles have the advantages over micron‐sized particles to typically provide higher
intracellular uptake and drug bioavailability. Emulsion techniques are commonly used …
intracellular uptake and drug bioavailability. Emulsion techniques are commonly used …
Lipid-polymer hybrid nanoparticles for controlled delivery of hydrophilic and lipophilic doxorubicin for breast cancer therapy
Background: Lipid polymer hybrid nanoparticles (LPHNPs) for the controlled delivery of
hydrophilic doxorubicin hydrochloride (DOX. HCl) and lipophilic DOX base have been …
hydrophilic doxorubicin hydrochloride (DOX. HCl) and lipophilic DOX base have been …
Modeling of the burst release from PLGA micro-and nanoparticles as function of physicochemical parameters and formulation characteristics
CR de Azevedo, M von Stosch, MS Costa… - International journal of …, 2017 - Elsevier
A substantial drug release from poly (lactic-co-glycolic) acid (PLGA) micro-and nanoparticles
can occur in the first hours of immersion, which is referred to as burst release. A strong burst …
can occur in the first hours of immersion, which is referred to as burst release. A strong burst …
CNS-targeting therapies for lysosomal storage diseases: current advances and challenges
MJ Edelmann, GHB Maegawa - Frontiers in molecular biosciences, 2020 - frontiersin.org
During the past decades, several therapeutic approaches have been developed and made
rapidly available for many patients afflicted with lysosomal storage disorders (LSDs), inborn …
rapidly available for many patients afflicted with lysosomal storage disorders (LSDs), inborn …