Double emulsion solvent evaporation techniques used for drug encapsulation

M Iqbal, N Zafar, H Fessi, A Elaissari - International journal of …, 2015 - Elsevier
Double emulsions are complex systems, also called “emulsions of emulsions”, in which the
droplets of the dispersed phase contain one or more types of smaller dispersed droplets …

Recent advances in protein and peptide drug delivery: a special emphasis on polymeric nanoparticles

A Patel, M Patel, X Yang, A K. Mitra - Protein and peptide letters, 2014 - benthamdirect.com
Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …

Gold nanoparticle should understand protein corona for being a clinical nanomaterial

F Charbgoo, M Nejabat, K Abnous, F Soltani… - Journal of controlled …, 2018 - Elsevier
Gold nanoparticles (AuNPs) have attracted great attention in biomedical fields due to their
unique properties. However, there are few reports on clinical trial of these nanoparticles. In …

The biomolecular corona of nanoparticles in circulating biological media

D Pozzi, G Caracciolo, L Digiacomo, V Colapicchioni… - Nanoscale, 2015 - pubs.rsc.org
When nanoparticles come into contact with biological media, they are covered by a
biomolecular 'corona', which confers a new identity to the particles. In all the studies reported …

Aerosol pulmonary immune engineering

ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …

Prediction of nanoparticles-cell association based on corona proteins and physicochemical properties

R Liu, W Jiang, CD Walkey, WCW Chan, Y Cohen - Nanoscale, 2015 - pubs.rsc.org
Cellular association of nanoparticles (NPs) in biological fluids is affected by proteins
adsorbed onto the NP surface, forming a “protein corona”, thereby impacting cellular …

Emulsion techniques for the production of pharmacological nanoparticles

R Jenjob, T Phakkeeree, F Seidi… - Macromolecular …, 2019 - Wiley Online Library
Nanoparticles have the advantages over micron‐sized particles to typically provide higher
intracellular uptake and drug bioavailability. Emulsion techniques are commonly used …

Lipid-polymer hybrid nanoparticles for controlled delivery of hydrophilic and lipophilic doxorubicin for breast cancer therapy

N Tahir, A Madni, A Correia, M Rehman… - International journal …, 2019 - Taylor & Francis
Background: Lipid polymer hybrid nanoparticles (LPHNPs) for the controlled delivery of
hydrophilic doxorubicin hydrochloride (DOX. HCl) and lipophilic DOX base have been …

Modeling of the burst release from PLGA micro-and nanoparticles as function of physicochemical parameters and formulation characteristics

CR de Azevedo, M von Stosch, MS Costa… - International journal of …, 2017 - Elsevier
A substantial drug release from poly (lactic-co-glycolic) acid (PLGA) micro-and nanoparticles
can occur in the first hours of immersion, which is referred to as burst release. A strong burst …

CNS-targeting therapies for lysosomal storage diseases: current advances and challenges

MJ Edelmann, GHB Maegawa - Frontiers in molecular biosciences, 2020 - frontiersin.org
During the past decades, several therapeutic approaches have been developed and made
rapidly available for many patients afflicted with lysosomal storage disorders (LSDs), inborn …