[HTML][HTML] The complex network of transcription factors, immune checkpoint inhibitors and stemness features in colorectal cancer: A recent update
Cancer immunity is regulated by several mechanisms that include co-stimulatory and/or co-
inhibitory molecules known as immune checkpoints expressed by the immune cells. In …
inhibitory molecules known as immune checkpoints expressed by the immune cells. In …
Multifunctional role of DEAD-box helicase 41 in innate immunity, hematopoiesis and disease
J Ma, SR Ross - Frontiers in Immunology, 2024 - frontiersin.org
DEAD-box helicases are multifunctional proteins participating in many aspects of cellular
RNA metabolism. DEAD-box helicase 41 (DDX41) in particular has pivotal roles in innate …
RNA metabolism. DEAD-box helicase 41 (DDX41) in particular has pivotal roles in innate …
DDX21, a host restriction factor of FMDV IRES-dependent translation and replication
SW Abdullah, J Wu, Y Zhang, M Bai, J Guan, X Liu… - Viruses, 2021 - mdpi.com
In cells, the contributions of DEAD-box helicases (DDXs), without which cellular life is
impossible, are of utmost importance. The extremely diverse roles of the nucleolar helicase …
impossible, are of utmost importance. The extremely diverse roles of the nucleolar helicase …
Unique role of DDX41, a DEAD-box type RNA helicase, in hematopoiesis and leukemogenesis
S Shinriki, H Matsui - Frontiers in oncology, 2022 - frontiersin.org
In myeloid malignancies including acute myeloid leukemia (AML) and myelodysplastic
syndromes (MDS), patient selection and therapeutic strategies are increasingly based on …
syndromes (MDS), patient selection and therapeutic strategies are increasingly based on …
DDX20: A Multifunctional Complex Protein
L He, J Yang, Y Hao, X Yang, X Shi, D Zhang, D Zhao… - Molecules, 2023 - mdpi.com
DEAD-box decap** enzyme 20 (DDX20) is a putative RNA-decap** enzyme that can
be identified by the conserved motif Asp–Glu–Ala–Asp (DEAD). Cellular processes involve …
be identified by the conserved motif Asp–Glu–Ala–Asp (DEAD). Cellular processes involve …
[HTML][HTML] CRIT: Identifying RNA-binding protein regulator in circRNA life cycle via non-negative matrix factorization
M Shao, S Hao, L Jiang, Y Cai, X Zhao, Q Chen… - … Therapy-Nucleic Acids, 2022 - cell.com
Circular RNAs (circRNAs) are endogenous non-coding RNAs that regulate gene expression
and participate in carcinogenesis. However, the RNA-binding proteins (RBPs) involved in …
and participate in carcinogenesis. However, the RNA-binding proteins (RBPs) involved in …
DEAD-box RNA helicases DDX3X and DDX5 as oncogenes or oncosuppressors: A network perspective
Simple Summary The transformation of a normal cell into a cancerous one is caused by the
deregulation of different metabolic pathways, involving a complex network of protein–protein …
deregulation of different metabolic pathways, involving a complex network of protein–protein …
DDX1 is a prognostic biomarker and correlates with immune infiltrations in hepatocellular carcinoma
M Yuan, J Xu, S Cao, S Sun - BMC immunology, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the leading lethal malignant tumors worldwide.
DEAD-box (DDX) family helicases are implicated in numerous human cancers. However …
DEAD-box (DDX) family helicases are implicated in numerous human cancers. However …
[HTML][HTML] Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway
DX Hu, QF Sun, L Xu, HD Lu, F Zhang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent
malignancies that seriously threaten people's health worldwide. DEAD-box helicase 51 …
malignancies that seriously threaten people's health worldwide. DEAD-box helicase 51 …
The 3′ terminal region of Zika virus RNA contains a conserved G-quadruplex and is unfolded by human DDX17
Zika virus (ZIKV) infection remains a worldwide concern, and currently no effective
treatments or vaccines are available. Novel therapeutics are an avenue of interest that could …
treatments or vaccines are available. Novel therapeutics are an avenue of interest that could …