[HTML][HTML] Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases

L Li, C Acioglu, RF Heary, S Elkabes - Brain, behavior, and immunity, 2021 - Elsevier
Central nervous system (CNS) innate immunity plays essential roles in infections,
neurodegenerative diseases, and brain or spinal cord injuries. Astrocytes and microglia are …

How does Zika virus cause microcephaly?

Z Wen, H Song, G Ming - Genes & development, 2017 - genesdev.cshlp.org
The re-emergence of Zika virus (ZIKV), a mosquito-borne and sexually transmitted flavivirus
circulating in> 70 countries and territories, poses a significant global threat to public health …

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

F Aubry, S Jacobs, M Darmuzey, S Lequime… - Nature …, 2021 - nature.com
The global emergence of Zika virus (ZIKV) revealed the unprecedented ability for a mosquito-
borne virus to cause congenital birth defects. A puzzling aspect of ZIKV emergence is that all …

Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes

PF Ledur, K Karmirian, CSG Pedrosa, LRQ Souza… - Scientific reports, 2020 - nature.com
Zika virus (ZIKV) has been extensively studied since it was linked to congenital
malformations, and recent research has revealed that astrocytes are targets of ZIKV …

Evolution of two major Zika virus lineages: implications for pathology, immune response, and vaccine development

JT Beaver, N Lelutiu, R Habib, I Skountzou - Frontiers in immunology, 2018 - frontiersin.org
Zika virus (ZIKV) became a public health emergency of global concern in 2015 due to its
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …

Zika virus infection: an update

P Ferraris, H Yssel, D Missé - Microbes and infection, 2019 - Elsevier
Since the ZIKV outbreak in Brazil in 2015, the scientific community has joined efforts to
gather more information on the epidemiology, clinical features and pathogenicity of the virus …

Zika virus hijacks stress granule proteins and modulates the host stress response

S Hou, A Kumar, Z Xu, AM Airo, I Stryapunina… - Journal of …, 2017 - journals.asm.org
Zika virus (ZIKV), a member of the Flaviviridae family, has recently emerged as an important
human pathogen with increasing economic and health impact worldwide. Because of its …

Neurotropic viruses, astrocytes, and COVID-19

P Tavčar, M Potokar, M Kolenc, M Korva… - Frontiers in cellular …, 2021 - frontiersin.org
At the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was
discovered in China, causing a new coronavirus disease, termed COVID-19 by the WHO on …

Differential virulence between Asian and African lineages of Zika virus

Y Simonin, D van Riel, P Van de Perre… - PLoS neglected …, 2017 - journals.plos.org
Zika virus (ZIKV) is a small enveloped positive-sense single-stranded RNA virus belonging
to the genus Flavivirus of the Flaviviridae family that has reemerged in recent years as a …

African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast

MA Sheridan, V Balaraman, DJ Schust, T Ezashi… - PloS one, 2018 - journals.plos.org
Zika virus (ZIKV) drew worldwide attention when a recent epidemic was linked to fetal
microcephaly. Here we used human embryonic stem cell derived trophoblasts as a model …