The polymer physics of single DNA confined in nanochannels

L Dai, CB Renner, PS Doyle - Advances in colloid and interface science, 2016 - Elsevier
In recent years, applications and experimental studies of DNA in nanochannels have
stimulated the investigation of the polymer physics of DNA in confinement. Recent advances …

Theory of wormlike polymer chains in confinement

JZY Chen - Progress in Polymer Science, 2016 - Elsevier
A semiflexible polymer chain shows characteristic local chain persistency and finite
extensibility. Confinement of such a polymer introduces a confinement length scale that …

Scaling theory of DNA confined in nanochannels and nanoslits

T Odijk - Physical Review E—Statistical, Nonlinear, and Soft …, 2008 - APS
A scaling analysis is presented of the statistics of long DNA confined in nanochannels and
nanoslits. It is argued that there are several regimes in between the de Gennes and Odijk …

Extended de Gennes regime of DNA confined in a nanochannel

L Dai, J Van Der Maarel, PS Doyle - Macromolecules, 2014 - ACS Publications
Scaling regimes for polymers confined to tubular channels are well established when the
channel cross-sectional dimension is either very small (Odjik regime) or large (classic de …

Free energy and extension of a semiflexible polymer in cylindrical confining geometries

Y Yang, TW Burkhardt, G Gompper - … Review E—Statistical, Nonlinear, and Soft …, 2007 - APS
We consider a long, semiflexible polymer with persistence length P and contour length L
fluctuating in a narrow cylindrical channel of diameter D. In the regime D⪡ P⪡ L the free …

Extension of DNA in a nanochannel as a rod-to-coil transition

DR Tree, Y Wang, KD Dorfman - Physical review letters, 2013 - APS
DNA confinement in nanochannels is emerging as an important tool for genomics and an
excellent platform for testing the theories of confined wormlike polymers. Using cutting-edge …

DNA confined in nanochannels: Hairpin tightening by entropic depletion

T Odijk - The Journal of chemical physics, 2006 - pubs.aip.org
A theory is presented of the elongation of double-stranded DNA confined in a nanochannel
based on a study of the formation of hairpins. A hairpin becomes constrained as it …

Influence of chain rigidity on the phase behavior of wormlike diblock copolymers

Y Jiang, JZY Chen - Physical review letters, 2013 - APS
We utilize the wormlike chain model in the framework of the self-consistent field theory to
investigate the influence of chain rigidity on the phase diagram of AB diblock copolymers in …

Electrokinetically-driven transport of DNA through focused ion beam milled nanofluidic channels

LD Menard, JM Ramsey - Analytical chemistry, 2013 - ACS Publications
The electrophoretically driven transport of double-stranded λ-phage DNA through focused
ion beam (FIB) milled nanochannels is described. Nanochannels were fabricated having …

Numerical study of linear and circular model DNA chains confined in a slit: metric and topological properties

C Micheletti, E Orlandini - Macromolecules, 2012 - ACS Publications
Advanced Monte Carlo simulations are used to study the effect of nanoslit confinement on
metric and topological properties of model DNA chains. We consider both linear and …