GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk

MA Connelly, JD Otvos, I Shalaurova… - Journal of translational …, 2017 - Springer
Background GlycA is a novel spectroscopic marker of systemic inflammation with low intra-
individual variability and other attributes favoring its clinical use in patients with chronic …

Human Serum/Plasma Glycoprotein Analysis by 1H-NMR, an Emerging Method of Inflammatory Assessment

R Fuertes-Martín, X Correig, JC Vallvé… - Journal of clinical …, 2020 - mdpi.com
Several studies suggest that variations in the concentration of plasma glycoproteins can
influence cellular changes in a large number of diseases. In recent years, proton nuclear …

Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism

F Pin, R Barreto, ME Couch, A Bonetto… - Journal of cachexia …, 2019 - Wiley Online Library
Background Cancer cachexia is a metabolic disorder involving perturbed energy balance
and altered mitochondrial function. Chemotherapy is a primary treatment option for many …

Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid …

DB Bartlett, LH Willis, CA Slentz, A Hoselton… - Arthritis research & …, 2018 - Springer
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease in which adults
have significant joint issues leading to poor health. Poor health is compounded by many …

[HTML][HTML] Meal-induced inflammation: postprandial insights from the Personalised REsponses to DIetary Composition Trial (PREDICT) study in 1000 participants

M Mazidi, AM Valdes, JM Ordovas, WL Hall… - The American journal of …, 2021 - Elsevier
Background Meal-induced metabolic changes trigger an acute inflammatory response,
contributing to chronic inflammation and associated diseases. Objectives We aimed to …

GlycA is a novel biomarker of inflammation and subclinical cardiovascular disease in psoriasis

AA Joshi, JB Lerman, TM Aberra, M Afshar… - Circulation …, 2016 - ahajournals.org
Rationale: GlycA, an emerging inflammatory biomarker, predicted cardiovascular events in
population-based studies. Psoriasis, an inflammatory disease associated with increased …

GlycA: a new biomarker for systemic inflammation and cardiovascular disease (CVD) risk assessment

RA Ballout, AT Remaley - Journal of laboratory and precision …, 2020 - pmc.ncbi.nlm.nih.gov
The GlycA test is a recently developed proton nuclear magnetic resonance (1H-NMR)
spectroscopy-based assay that has been gaining increased interest as a serum biomarker …

Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability

KM Huffman, R Jessee, B Andonian, BN Davis… - Arthritis research & …, 2017 - Springer
Background To identify molecular alterations in skeletal muscle in rheumatoid arthritis (RA)
that may contribute to ongoing disability in RA. Methods Persons with seropositive or erosive …

Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer's disease

N Liang, K Nho, JW Newman, M Arnold, K Huynh… - Scientific reports, 2024 - nature.com
Inflammation is an important factor in Alzheimer's disease (AD). An NMR measurement in
plasma, glycoprotein acetyls (GlycA), captures the overall level of protein production and …

Characterization of 1H NMR Plasma Glycoproteins as a New Strategy To Identify Inflammatory Patterns in Rheumatoid Arthritis

R Fuertes-Martín, D Taverner, JC Vallvé… - Journal of Proteome …, 2018 - ACS Publications
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease associated with a
high index of morbidity and mortality from cardiovascular diseases. We used 1H NMR to …