The epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor of the ErbB family
that is abnormally activated in many epithelial tumors. Receptor activation leads to …

Abstract Learning Objectives After completing this course, the reader will be able to: Explain
the molecular biology of epidermal growth factor receptor (EGFR) function in malignant cells …

The human epidermal growth factor receptor (HER1/EGFR) is dysregulated in many solid
tumors, making it an attractive target for anticancer therapy. A number of agents that target …

Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the clinical and pathological characteristics of the cutaneous rash secondary to …

Despite aggressive surgical and chemotherapeutic interventions, non-small-cell lung cancer
(NSCLC) is the leading cause of cancer-related death in men and women with overall cure …

The epidermal growth factor receptor (EGFR) is overexpressed in many solid tumours.
Targeting EGFR is emerging as a potential strategy to incorporate into cancer treatment …

The epidermal growth factor receptor (EGFR) is a member of the erbB family of tyrosine
kinase receptors (RTK). The EGFR is involved in cell proliferation, metastasis and …

From the early experience with tamoxifen to the current use of Herceptin®, targeted therapy
has been proven to be an important part of breast cancer (BC) treatment. In the last decade …

It is well known that growth factors play an important role in normal cell proliferation by
means of stimulation of growth factor receptors located on the surface of cells. Tumor cells …

Nygren P, Larsson R (Section of Oncology and Section of Clinical Pharmacology, University
Hospital, Uppsala, Sweden). Overview of the clinical efficacy of investigational anticancer …