Cancer is a severe public health issue that is a leading cause of mortality globally. It is also
an impediment to improving life expectancy worldwide. Furthermore, the global burden of …

It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to
such an abnormally rapid proliferation rate, cancer cells constantly encounter the limits of …

Aims This study aims to explore the function and mechanism of G Protein-coupled receptor
class C group 5 member A (GPRC5A) in docetaxel-resistance and liver metastasis of breast …

Sonodynamic therapy (SDT) is a noninvasive technique for local antitumor treatment;
however, its clinical application is often limited by the low tumor accumulation of SDT …

Autophagy is crucial for maintaining cellular energy homeostasis and for cells to adapt to
nutrient deficiency, and nutrient sensors regulating autophagy have been reported …

The regulation of intracellular ions' overload to interrupt normal bioprocesses and cause cell
death has been developed as an efficient strategy (named as ion-interference therapy/IIT) to …

Cell division and cell death are fundamental processes governing growth and development
across the tree of life. This relationship represents an evolutionary link between cell cycle …

Autophagy is an explicit cellular process to deliver dissimilar cytoplasmic misfolded proteins,
lipids and damaged organelles to the lysosomes for degradation and elimination. The …

With global population aging, age-related diseases, especially sarcopenia, have attracted
much attention in recent years. Characterized by low muscle strength, low muscle quantity or …

Coupling materials chemistry systems to biological processes is a promising way to
rationally modulate lysosomal functions. A proton‐driven dynamic assembly of a DNA …