Owing to advances in radiotherapy, the physical properties of radiation can be optimized to
enable individualized treatment; however, optimization is rarely based on biological …

Over the last few years, progress has been made across the nanomedicine landscape, in
particular, the invention of contemporary nanostructures for cancer diagnosis and …

In multiple cancer types, high tumor mutational burden (TMB) is associated with longer
survival after treatment with immune checkpoint inhibitors (ICIs). The association of TMB with …

Background Until recently, patients who have the same type and stage of cancer all receive
the same treatment. It has been established, however, that individuals with the same …

Although the orbit is a small anatomical space, the wide range of structures present within it
are often the site of origin of various tumours and tumour-like conditions, both in adults and …

Genetic investigation of tumor heterogeneity and clonal evolution in solid cancers could be
assisted by the analysis of liquid biopsies. However, tumors of various entities might release …

Fully integrated positron emission tomography (PET)/magnetic resonance imaging (MRI)
scanners have been available for a few years. Since then, the number of scanner …

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease arising
from the mucosa of the upper aerodigestive tract. Despite multimodality treatments …

Purpose Definitive radiochemotherapy (RCTX) with curative intent is one of the standard
treatment options in patients with locally advanced head and neck squamous cell carcinoma …

Simple Summary Immunotherapy has prompted a dramatic change in the management of
head and neck squamous cell carcinoma (HNSCC), but the percentage of patients …