[HTML][HTML] Deep brain stimulation of thalamus for epilepsy

RS Fisher - Neurobiology of Disease, 2023‏ - Elsevier
Neuromodulation (neurostimulation) is a relatively new and rapidly growing treatment for
refractory epilepsy. Three varieties are approved in the US: vagus nerve stimulation (VNS) …

Practical considerations in epilepsy neurostimulation

HD Simpson, A Schulze‐Bonhage, GD Cascino… - …, 2022‏ - Wiley Online Library
Neuromodulation is a key therapeutic tool for clinicians managing patients with drug‐
resistant epilepsy. Multiple devices are available with long‐term follow‐up and real‐world …

Brain‐responsive corticothalamic stimulation in the pulvinar nucleus for the treatment of regional neocortical epilepsy: a case series

D Burdette, EA Mirro, M Lawrence, SE Patra - Epilepsia Open, 2021‏ - Wiley Online Library
Drug‐resistant focal epilepsy with regional neocortical seizure onsets originating from the
posterior quadrant can be particularly difficult to treat with resective surgery due to the …

Centromedian thalamic deep brain stimulation for drug-resistant epilepsy: single-center experience

JC Yang, KL Bullinger, F Isbaine, A Alwaki, E Opri… - Journal of …, 2022‏ - thejns.org
OBJECTIVE Neuromodulation of the centromedian nucleus of the thalamus (CM) has
unclear effectiveness in the treatment of drug-resistant epilepsy. Prior reports suggest that it …

[HTML][HTML] Brain stimulation treatments in epilepsy: basic mechanisms and clinical advances

TJ Foutz, M Wong - biomedical journal, 2022‏ - Elsevier
Drug-resistant epilepsy, characterized by ongoing seizures despite appropriate trials of anti-
seizure medications, affects approximately one-third of people with epilepsy. Brain …

Responsive neurostimulation targeting the anterior, centromedian and pulvinar thalamic nuclei and the detection of electrographic seizures in pediatric and young …

CP Beaudreault, CR Muh, A Naftchi… - Frontiers in Human …, 2022‏ - frontiersin.org
Background Responsive neurostimulation (RNS System) has been utilized as a treatment
for intractable epilepsy. The RNS System delivers stimulation in response to detected …

Case report: responsive neurostimulation of the centromedian thalamic nucleus for the detection and treatment of seizures in pediatric primary generalized epilepsy

WP Welch, JL Hect, TJ Abel - Frontiers in Neurology, 2021‏ - frontiersin.org
Up to 20% of pediatric patients with primary generalized epilepsy (PGE) will not respond
effectively to medication for seizure control. Responsive neurostimulation (RNS) is a …

[HTML][HTML] Centromedian thalamic nucleus with or without anterior thalamic nucleus deep brain stimulation for epilepsy in children and adults: a retrospective case series

JL Alcala-Zermeno, NM Gregg, EC Wirrell, M Stead… - Seizure, 2021‏ - Elsevier
The centromedian (CM) and anterior nucleus of the thalamus (ANT) are deep brain
stimulation (DBS) targets for management of generalized, and focal drug resistant epilepsy …

Responsive neurostimulation of the thalamus for the treatment of refractory epilepsy

JA Roa, M Abramova, M Fields… - Frontiers in Human …, 2022‏ - frontiersin.org
Introduction One-third of patients with epilepsy continue to have seizures despite
antiepileptic medications. Some of these refractory patients may not be candidates for …

A multicenter retrospective study of patients treated in the thalamus with responsive neurostimulation

MC Fields, O Eka, C Schreckinger, P Dugan… - Frontiers in …, 2023‏ - frontiersin.org
Introduction For drug resistant epilepsy patients who are either not candidates for resective
surgery or have already failed resective surgery, neuromodulation is a promising option …