Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …
various physiological and pathological processes. Their biogenesis involves four key steps …
Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
Fingerprint profiling of glycans on extracellular vesicles via lectin-induced aggregation strategy for precise cancer diagnostics
G Zhang, X Huang, Y Gong, Y Ding… - Journal of the …, 2024 - ACS Publications
Extracellular vesicles (EVs) harbor abundant glycans that mediate various functions, such as
intercellular communication and disease advancement, which play significant roles in …
intercellular communication and disease advancement, which play significant roles in …
Protein glycosylation in extracellular vesicles: Structural characterization and biological functions
Extracellular vesicles (EVs) are lipid bilayer-enclosed particles involved in intercellular
communication, delivery of biomolecules from donor to recipient cells, cellular disposal and …
communication, delivery of biomolecules from donor to recipient cells, cellular disposal and …
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5
J Wu, Z Tan, H Li, M Lin, Y Jiang, L Liang… - Journal of Pineal …, 2021 - Wiley Online Library
Melatonin helps to maintain circadian rhythm, exerts anticancer activity, and plays key roles
in regulation of glucose homeostasis and energy metabolism. Glycosylation, a form of …
in regulation of glucose homeostasis and energy metabolism. Glycosylation, a form of …
From exosome biogenesis to absorption: key takeaways for cancer research
NCH Lau, JWP Yam - Cancers, 2023 - mdpi.com
Simple Summary Exosomes are nanometer-sized vesicles released by different cells that
are important in the normal functioning of the body. In cancer, exosomes have been found to …
are important in the normal functioning of the body. In cancer, exosomes have been found to …
[HTML][HTML] The hidden potential of glycomarkers: Glycosylation studies in the service of cancer diagnosis and treatment
Abstract Changes in the glycosylation process appear early in carcinogenesis and evolve
with the growth and spread of cancer. The correlation of the characteristic glycosylation …
with the growth and spread of cancer. The correlation of the characteristic glycosylation …
Tumor-derived nanoseeds condition the soil for metastatic organotropism
Primary tumors secrete a variety of factors to turn distant microenvironments into favorable
and fertile 'soil'for subsequent metastases. Among these 'seeding'factors that initiate pre …
and fertile 'soil'for subsequent metastases. Among these 'seeding'factors that initiate pre …
Comprehensive review of MS‐based studies on N‐glycoproteome and N‐glycome of extracellular vesicles
Y Li, J Wang, W Chen, H Lu, Y Zhang - Proteomics, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed particles that can be released by all
type of cells. Whereas, as one of the most common post‐translational modifications …
type of cells. Whereas, as one of the most common post‐translational modifications …
Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/miR-1-3p axis in bladder cancer
Background Abnormal glycosylation in a variety of cancer types is involved in tumor
progression and chemoresistance. Glycosyltransferase C1GALT1, the key enzyme in …
progression and chemoresistance. Glycosyltransferase C1GALT1, the key enzyme in …