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Astrocytes in human central nervous system diseases: a frontier for new therapies
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
Function and therapeutic value of astrocytes in neurological diseases
Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
Neuroinflammation: an astrocyte perspective
Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles
in health and disease. Recent technologies have uncovered the functional heterogeneity of …
in health and disease. Recent technologies have uncovered the functional heterogeneity of …
Astrocyte crosstalk in CNS inflammation
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
Inflammation in Parkinson's disease: mechanisms and therapeutic implications
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …
[HTML][HTML] Neuroinflammation and Parkinson's disease—from neurodegeneration to therapeutic opportunities
B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
[HTML][HTML] Microglia and astrocyte dysfunction in parkinson's disease
While glia are essential for regulating the homeostasis in the normal brain, their dysfunction
contributes to neurodegeneration in many brain diseases, including Parkinson's disease …
contributes to neurodegeneration in many brain diseases, including Parkinson's disease …
[HTML][HTML] Glutamate-induced excitotoxicity in Parkinson's disease: The role of glial cells
Glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamate
transmission efficiency depends on the correct functionality and expression of a plethora of …
transmission efficiency depends on the correct functionality and expression of a plethora of …
Brain‐targeted liposomes loaded with monoclonal antibodies reduce alpha‐synuclein aggregation and improve behavioral symptoms in Parkinson's disease
Monoclonal antibodies (mAbs) hold promise in treating Parkinson's disease (PD), although
poor delivery to the brain hinders their therapeutic application. In the current study, it is …
poor delivery to the brain hinders their therapeutic application. In the current study, it is …
Reactive astrocytes in neurodegenerative diseases
K Li, J Li, J Zheng, S Qin - Aging and disease, 2019 - pmc.ncbi.nlm.nih.gov
Astrocytes, the largest and most numerous glial cells in the central nervous system (CNS),
play a variety of important roles in regulating homeostasis, increasing synaptic plasticity and …
play a variety of important roles in regulating homeostasis, increasing synaptic plasticity and …